Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer

We validated an 18-gene classifier (GC) initially developed to predict local/regional recurrence after mastectomy in estimating distant metastasis risk. The 18-gene scoring algorithm defines scores as:

Saved in:
Bibliographic Details
Published in:PloS one 2017-09, Vol.12 (9), p.e0184372-e0184372
Main Authors: Cheng, Skye Hung-Chun, Huang, Tzu-Ting, Cheng, Yu-Hao, Tan, Tee Benita Kiat, Horng, Chen-Fang, Wang, Yong Alison, Brian, Nicholas Shannon, Shih, Li-Sun, Yu, Ben-Long
Format: Article
Language:English
Subjects:
Adult
Aged
Biomarkers
Biomarkers, Tumor
Breast cancer
Breast Neoplasms - genetics
Breast Neoplasms - mortality
Breast Neoplasms - pathology
Breast Neoplasms - therapy
Cancer
Cancer therapies
Chemotherapy
Classifiers
Combined Modality Therapy
Developing countries
Female
Gene expression
Gene Expression Profiling
Health risks
Hospitals
Humans
LDCs
Mammography
Mastectomy
Medical prognosis
Medical screening
Medicine
Medicine and Health Sciences
Metastases
Metastasis
Middle Aged
Multivariate analysis
Neoplasm Grading
Neoplasm Metastasis
Neoplasm Staging
Patients
Prognosis
Proportional Hazards Models
Radiation therapy
Regional development
Reproducibility of Results
Risk
Risk groups
Surgery
Tissues
Womens health
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We validated an 18-gene classifier (GC) initially developed to predict local/regional recurrence after mastectomy in estimating distant metastasis risk. The 18-gene scoring algorithm defines scores as:
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0184372