Pediatric melioidosis in Sarawak, Malaysia: Epidemiological, clinical and microbiological characteristics

Melioidosis is a serious, and potentially fatal community-acquired infection endemic to northern Australia and Southeast Asia, including Sarawak, Malaysia. The disease, caused by the usually intrinsically aminoglycoside-resistant Burkholderia pseudomallei, most commonly affects adults with predispos...

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Bibliographic Details
Published in:PLoS neglected tropical diseases 2017-06, Vol.11 (6), p.e0005650-e0005650
Main Authors: Mohan, Anand, Podin, Yuwana, Tai, Nickson, Chieng, Chae-Hee, Rigas, Vanessa, Machunter, Barbara, Mayo, Mark, Wong, Desiree, Chien, Su-Lin, Tan, Lee-See, Goh, Charles, Bantin, Reginal, Mijen, Alexander, Chua, Wen-Yi, Hii, King-Ching, Wong, See-Chang, Ngian, Hie-Ung, Wong, Jin-Shyan, Hashim, Jamilah, Currie, Bart J, Ooi, Mong-How
Format: Article
Language:English
Subjects:
Adolescent
Adults
Aminoglycoside antibiotics
Antibiotics
Bacteremia
Biology and Life Sciences
Burkholderia
Care and treatment
Child
Child, Preschool
Children
Clinical isolates
Diagnosis
Diseases
Epidemiology
Fatalities
Female
Gentamicin
Glands
Hospitals
Humans
Incidence
Infant
Infant, Newborn
Infections
Joints
Joints (timber)
Lungs
Lymph
Lymph nodes
Malaysia - epidemiology
Male
Medical research
Medicine
Medicine and Health Sciences
Melioidosis
Melioidosis - epidemiology
Melioidosis - pathology
Pathology
Pediatric diseases
Pediatrics
Prevalence studies (Epidemiology)
Prospective Studies
Pseudomonas infections
Rain
Retrospective Studies
Risk analysis
Risk factors
Sequencing
Spleen
Strains
Studies
Time Factors
Tropical diseases
Virulence
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Items that cite this one
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Description
Summary:Melioidosis is a serious, and potentially fatal community-acquired infection endemic to northern Australia and Southeast Asia, including Sarawak, Malaysia. The disease, caused by the usually intrinsically aminoglycoside-resistant Burkholderia pseudomallei, most commonly affects adults with predisposing risk factors. There are limited data on pediatric melioidosis in Sarawak. A part prospective, part retrospective study of children aged
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0005650