Post-term growth and cognitive development at 5 years of age in preterm children: Evidence from a prospective population-based cohort

While the effects of growth from birth to expected term on the subsequent development of preterm children has attracted plentiful attention, less is known about the effects of post-term growth. We aimed to delineate distinct patterns of post-term growth and to determine their association with the co...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2017-03, Vol.12 (3), p.e0174645-e0174645
Main Authors: Simon, Laure, Nusinovici, Simon, Flamant, Cyril, Cariou, Bertrand, Rouger, Valérie, Gascoin, Géraldine, Darmaun, Dominique, Rozé, Jean-Christophe, Hanf, Matthieu
Format: Article
Language:English
Subjects:
Abnormalities
Age
Agricultural management
Agricultural research
Agronomy
Algorithms
Anomalies
Antibiotics
Bacteria
Bacterial infections
Biology and Life Sciences
Birth Weight
Body mass
Body Mass Index
Brain
Breast feeding
Breastfeeding & lactation
Cardiovascular diseases
Child development
Child Development - physiology
Child, Preschool
Children
Children & youth
Cognition - physiology
Cognitive ability
Cognitive development
Complications
Corticoids
Corticosteroids
Data acquisition
Data collection
Drugs
Economic conditions
Epidemiology
Female
Fetuses
Gender
Generalized linear models
Gestational Age
Growth
Health aspects
Health risks
Hemorrhage
Heterogeneity
Hospitals
Humans
Hypertension
Identification methods
Imaging techniques
Infant
Infant, Newborn
Infant, Premature - growth & development
Infant, Premature - psychology
Infants
Infections
Infectious diseases
Intensive care
Intensive care units
Intubation
Learning - physiology
Life Sciences
Lift
Logistic Models
Magnetic resonance imaging
Male
Mathematical models
Medicine
Medicine and Health Sciences
Mortality
Neuroimaging
Newborn babies
NMR
Nuclear magnetic resonance
Nutrition
People and Places
Pharmacology
Population
Population studies
Pregnancy
Premature birth
Premature infants
Prospective Studies
Risk factors
Skull
Studies
Surgery
Trajectories
Ultrasonic imaging
Ultrasound
Ventricle
Visual perception
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:While the effects of growth from birth to expected term on the subsequent development of preterm children has attracted plentiful attention, less is known about the effects of post-term growth. We aimed to delineate distinct patterns of post-term growth and to determine their association with the cognitive development of preterm children. Data from a prospective population-based cohort of 3,850 surviving infants born at less than 35 weeks of gestational age were used. Growth was assessed as the Body Mass Index (BMI) Z-scores at 3, 9, 18, 24, 36, 48, and 60 months. Cognitive development at five years of age was evaluated by the Global School Adaptation score (GSA). Latent class analysis was implemented to identify distinct growth patterns and logistic regressions based on propensity matching were used to evaluate the relationship between identified growth trajectories and cognitive development. Four patterns of post-term growth were identified: a normal group with a Z-score consistently around zero during childhood (n = 2,469; 64%); a group with an early rapid rise in the BMI Z-score, but only up to 2 years of age (n = 195; 5%); a group with a slow yet steady rise in the BMI Z-score during childhood (n = 510; 13%); and a group with a negative Z-score growth until 3 years of age (n = 676; 18%). The group with a slow yet steady rise in the BMI Z-score was significantly associated with low GSA scores. Our findings indicate heterogeneous post-term growth of preterm children, with potential for association with their cognitive development.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0174645