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The association between frequent alcohol drinking and opioid consumption after abdominal surgery: A retrospective analysis
It is perceived that patients with a history of frequent alcohol consumption require more opioids for postoperative pain control and experience less postoperative nausea and vomiting than patients without such a history. However, there is scarce evidence supporting this notion. The aim of this study...
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| Published in: | PloS one 2017-03, Vol.12 (3), p.e0171275-e0171275 |
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| creator | Kao, Sheng-Chin Tsai, Hsin-I Cheng, Chih-Wen Lin, Ta-Wei Chen, Chien-Chuan Lin, Chia-Shiang |
| description | It is perceived that patients with a history of frequent alcohol consumption require more opioids for postoperative pain control and experience less postoperative nausea and vomiting than patients without such a history. However, there is scarce evidence supporting this notion. The aim of this study was to assess association between frequent alcohol consumption and opioid requirement for postoperative pain control and occurrence of postoperative nausea and vomiting.
The medical records for 4143 patients using intravenous patient-control analgesia with opioids after abdominal surgery between January 2010 and September 2013 were obtained, and associations were sought between the cumulative opioid consumption (in intravenous morphine equivalence) per body weight (mg/kg) in the first 2 days after abdominal operation and several demographic and clinical variables by multiple regression analysis. The association between the occurrence of postoperative nausea and vomiting and several demographic and clinical variables was also sought by multiple logistic regression analysis.
Frequent alcohol drinking, among other previously reported factors, was associated with increased opioid consumption for postoperative pain control (p < 0.001). The estimate effect of frequent alcohol drinking was 0.117 mg/kg. Frequent alcohol drinking was also associated with decreased risks of postoperative nausea (odds ratio = 0.59, p = 0.003) and vomiting (odds ratio = 0.49, p = 0.026).
Frequent alcohol drinking was associated with increased opioid consumption for postoperative pain control and decreased risks of postoperative nausea and vomiting after abdominal surgery. |
| doi_str_mv | 10.1371/journal.pone.0171275 |
| format | article |
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The medical records for 4143 patients using intravenous patient-control analgesia with opioids after abdominal surgery between January 2010 and September 2013 were obtained, and associations were sought between the cumulative opioid consumption (in intravenous morphine equivalence) per body weight (mg/kg) in the first 2 days after abdominal operation and several demographic and clinical variables by multiple regression analysis. The association between the occurrence of postoperative nausea and vomiting and several demographic and clinical variables was also sought by multiple logistic regression analysis.
Frequent alcohol drinking, among other previously reported factors, was associated with increased opioid consumption for postoperative pain control (p < 0.001). The estimate effect of frequent alcohol drinking was 0.117 mg/kg. Frequent alcohol drinking was also associated with decreased risks of postoperative nausea (odds ratio = 0.59, p = 0.003) and vomiting (odds ratio = 0.49, p = 0.026).
Frequent alcohol drinking was associated with increased opioid consumption for postoperative pain control and decreased risks of postoperative nausea and vomiting after abdominal surgery.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0171275</identifier><identifier>PMID: 28301483</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Abdomen - surgery ; Abdominal surgery ; Adult ; Aged ; Aged, 80 and over ; Alcohol Drinking ; Alcohol use ; Alcohols ; Analgesia ; Analgesia, Patient-Controlled ; Analgesics, Opioid - administration & dosage ; Analysis ; Biology and Life Sciences ; Body weight ; Consumption ; Demographic variables ; Demographics ; Dosage and administration ; Drinking ; Drinking (Alcoholic beverages) ; Drinking behavior ; Female ; Health aspects ; Humans ; Intravenous administration ; Kinases ; Male ; Medical records ; Medicine and Health Sciences ; Middle Aged ; Morphine ; Multiple regression analysis ; Narcotics ; Nausea ; Opioids ; Pain ; Pain management ; Pain perception ; Pain, Postoperative - drug therapy ; Patient satisfaction ; Patients ; Postoperative Nausea and Vomiting - etiology ; Regression analysis ; Retrospective Studies ; Rodents ; Surgery ; Vomiting</subject><ispartof>PloS one, 2017-03, Vol.12 (3), p.e0171275-e0171275</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Kao et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2017 Kao et al 2017 Kao et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c751t-df7496949a48fbc9fb76e44030dce7c885fc8c6a240fc6f8d2714f1066df95633</citedby><cites>FETCH-LOGICAL-c751t-df7496949a48fbc9fb76e44030dce7c885fc8c6a240fc6f8d2714f1066df95633</cites><orcidid>0000-0003-1035-7815</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1878126357/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1878126357?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,315,733,786,790,891,25783,27957,27958,37047,37048,44625,53827,53829,75483</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28301483$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Ma, Zheng-Liang</contributor><creatorcontrib>Kao, Sheng-Chin</creatorcontrib><creatorcontrib>Tsai, Hsin-I</creatorcontrib><creatorcontrib>Cheng, Chih-Wen</creatorcontrib><creatorcontrib>Lin, Ta-Wei</creatorcontrib><creatorcontrib>Chen, Chien-Chuan</creatorcontrib><creatorcontrib>Lin, Chia-Shiang</creatorcontrib><title>The association between frequent alcohol drinking and opioid consumption after abdominal surgery: A retrospective analysis</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>It is perceived that patients with a history of frequent alcohol consumption require more opioids for postoperative pain control and experience less postoperative nausea and vomiting than patients without such a history. However, there is scarce evidence supporting this notion. The aim of this study was to assess association between frequent alcohol consumption and opioid requirement for postoperative pain control and occurrence of postoperative nausea and vomiting.
The medical records for 4143 patients using intravenous patient-control analgesia with opioids after abdominal surgery between January 2010 and September 2013 were obtained, and associations were sought between the cumulative opioid consumption (in intravenous morphine equivalence) per body weight (mg/kg) in the first 2 days after abdominal operation and several demographic and clinical variables by multiple regression analysis. The association between the occurrence of postoperative nausea and vomiting and several demographic and clinical variables was also sought by multiple logistic regression analysis.
Frequent alcohol drinking, among other previously reported factors, was associated with increased opioid consumption for postoperative pain control (p < 0.001). The estimate effect of frequent alcohol drinking was 0.117 mg/kg. Frequent alcohol drinking was also associated with decreased risks of postoperative nausea (odds ratio = 0.59, p = 0.003) and vomiting (odds ratio = 0.49, p = 0.026).
Frequent alcohol drinking was associated with increased opioid consumption for postoperative pain control and decreased risks of postoperative nausea and vomiting after abdominal surgery.</description><subject>Abdomen - surgery</subject><subject>Abdominal surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Alcohol Drinking</subject><subject>Alcohol use</subject><subject>Alcohols</subject><subject>Analgesia</subject><subject>Analgesia, Patient-Controlled</subject><subject>Analgesics, Opioid - administration & dosage</subject><subject>Analysis</subject><subject>Biology and Life Sciences</subject><subject>Body weight</subject><subject>Consumption</subject><subject>Demographic variables</subject><subject>Demographics</subject><subject>Dosage and administration</subject><subject>Drinking</subject><subject>Drinking (Alcoholic beverages)</subject><subject>Drinking behavior</subject><subject>Female</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Intravenous administration</subject><subject>Kinases</subject><subject>Male</subject><subject>Medical records</subject><subject>Medicine and Health Sciences</subject><subject>Middle Aged</subject><subject>Morphine</subject><subject>Multiple regression analysis</subject><subject>Narcotics</subject><subject>Nausea</subject><subject>Opioids</subject><subject>Pain</subject><subject>Pain management</subject><subject>Pain perception</subject><subject>Pain, Postoperative - drug therapy</subject><subject>Patient satisfaction</subject><subject>Patients</subject><subject>Postoperative Nausea and Vomiting - etiology</subject><subject>Regression analysis</subject><subject>Retrospective Studies</subject><subject>Rodents</subject><subject>Surgery</subject><subject>Vomiting</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNk8tuEzEUhkcIREvhDRCMhIRgkWCPr8MCKaq4RKpUCQpby_EcJy4TO9ieQnh6nCatEtRFNQuP7O__fXwuVfUcozEmAr-7DEP0uh-vgocxwgI3gj2ojnFLmhFvEHm4939UPUnpEiFGJOePq6NGEoSpJMfV34sF1DqlYJzOLvh6Bvk3gK9thF8D-Fzr3oRF6OsuOv_T-XmtfVeHlQuuq03waViuroXaZoi1nnVh6UpcdRriHOL6fT2pI-QY0gpMdlfltnK6Ti49rR5Z3Sd4tltPqu-fPl6cfhmdnX-enk7ORkYwnEedFbTlLW01lXZmWjsTHChFBHUGhJGSWSMN1w1F1nAru0ZgajHivLMt44ScVC-3vqs-JLVLW1JYCokbTpgoxHRLdEFfqlV0Sx3XKminrjdCnCsdszM9KCQ74JhyMxMN1RQ07TRuGHAGrEWGF68Pu9uG2RJKiD5H3R-YHp54t1DzcKUYYbRhuBi82RnEUCqQslq6ZKDvtYcwbOKWWHBKxX1QUeBWks0TX_2H3p2IHTXX5a3O21BCNBtTNaGSCVb8aKHGd1Dl62DpSkuAdWX_QPD2QFCYDH_yXA8pqem3r_dnz38csq_32AXoPi9S6IdNP6ZDkG5BU_owRbC39cBIbabpJhtqM01qN01F9mK_lreim_Eh_wAL5hwi</recordid><startdate>20170316</startdate><enddate>20170316</enddate><creator>Kao, Sheng-Chin</creator><creator>Tsai, Hsin-I</creator><creator>Cheng, Chih-Wen</creator><creator>Lin, Ta-Wei</creator><creator>Chen, Chien-Chuan</creator><creator>Lin, Chia-Shiang</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-1035-7815</orcidid></search><sort><creationdate>20170316</creationdate><title>The association between frequent alcohol drinking and opioid consumption after abdominal surgery: A retrospective analysis</title><author>Kao, Sheng-Chin ; Tsai, Hsin-I ; Cheng, Chih-Wen ; Lin, Ta-Wei ; Chen, Chien-Chuan ; Lin, Chia-Shiang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c751t-df7496949a48fbc9fb76e44030dce7c885fc8c6a240fc6f8d2714f1066df95633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Abdomen - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kao, Sheng-Chin</au><au>Tsai, Hsin-I</au><au>Cheng, Chih-Wen</au><au>Lin, Ta-Wei</au><au>Chen, Chien-Chuan</au><au>Lin, Chia-Shiang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The association between frequent alcohol drinking and opioid consumption after abdominal surgery: A retrospective analysis</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2017-03-16</date><risdate>2017</risdate><volume>12</volume><issue>3</issue><spage>e0171275</spage><epage>e0171275</epage><pages>e0171275-e0171275</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><notes>Conceptualization: SCK HIT CWC.Data curation: SCK.Investigation: SCK HIT CWC TWL.Methodology: SCK CSL CCC.Project administration: SCK CSL.Supervision: SCK CSL.Visualization: SCK HIT.Writing – original draft: SCK HIT.Writing – review & editing: CSL CCC.</notes><notes>Competing Interests: The authors have declared that no competing interests exist.</notes><abstract>It is perceived that patients with a history of frequent alcohol consumption require more opioids for postoperative pain control and experience less postoperative nausea and vomiting than patients without such a history. However, there is scarce evidence supporting this notion. The aim of this study was to assess association between frequent alcohol consumption and opioid requirement for postoperative pain control and occurrence of postoperative nausea and vomiting.
The medical records for 4143 patients using intravenous patient-control analgesia with opioids after abdominal surgery between January 2010 and September 2013 were obtained, and associations were sought between the cumulative opioid consumption (in intravenous morphine equivalence) per body weight (mg/kg) in the first 2 days after abdominal operation and several demographic and clinical variables by multiple regression analysis. The association between the occurrence of postoperative nausea and vomiting and several demographic and clinical variables was also sought by multiple logistic regression analysis.
Frequent alcohol drinking, among other previously reported factors, was associated with increased opioid consumption for postoperative pain control (p < 0.001). The estimate effect of frequent alcohol drinking was 0.117 mg/kg. Frequent alcohol drinking was also associated with decreased risks of postoperative nausea (odds ratio = 0.59, p = 0.003) and vomiting (odds ratio = 0.49, p = 0.026).
Frequent alcohol drinking was associated with increased opioid consumption for postoperative pain control and decreased risks of postoperative nausea and vomiting after abdominal surgery.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>28301483</pmid><doi>10.1371/journal.pone.0171275</doi><tpages>e0171275</tpages><orcidid>https://orcid.org/0000-0003-1035-7815</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2017-03, Vol.12 (3), p.e0171275-e0171275 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1878126357 |
| source | Publicly Available Content Database; PubMed Central |
| subjects | Abdomen - surgery Abdominal surgery Adult Aged Aged, 80 and over Alcohol Drinking Alcohol use Alcohols Analgesia Analgesia, Patient-Controlled Analgesics, Opioid - administration & dosage Analysis Biology and Life Sciences Body weight Consumption Demographic variables Demographics Dosage and administration Drinking Drinking (Alcoholic beverages) Drinking behavior Female Health aspects Humans Intravenous administration Kinases Male Medical records Medicine and Health Sciences Middle Aged Morphine Multiple regression analysis Narcotics Nausea Opioids Pain Pain management Pain perception Pain, Postoperative - drug therapy Patient satisfaction Patients Postoperative Nausea and Vomiting - etiology Regression analysis Retrospective Studies Rodents Surgery Vomiting |
| title | The association between frequent alcohol drinking and opioid consumption after abdominal surgery: A retrospective analysis |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-21T11%3A08%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20association%20between%20frequent%20alcohol%20drinking%20and%20opioid%20consumption%20after%20abdominal%20surgery:%20A%20retrospective%20analysis&rft.jtitle=PloS%20one&rft.au=Kao,%20Sheng-Chin&rft.date=2017-03-16&rft.volume=12&rft.issue=3&rft.spage=e0171275&rft.epage=e0171275&rft.pages=e0171275-e0171275&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0171275&rft_dat=%3Cgale_plos_%3EA485757884%3C/gale_plos_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c751t-df7496949a48fbc9fb76e44030dce7c885fc8c6a240fc6f8d2714f1066df95633%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1878126357&rft_id=info:pmid/28301483&rft_galeid=A485757884&rfr_iscdi=true |