Clinical Characteristics of Young Type 2 Diabetes Patients with Atherosclerosis

The prevalence of type 2 diabetes is increasing rapidly in the young population. The clinical characteristics and risk factors for young type 2 diabetes patients with atherosclerosis are not fully explicated. The aim of the present study was to investigate various clinical and biochemical characteri...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2016-07, Vol.11 (7), p.e0159055-e0159055
Main Authors: Yang, Wenjia, Cai, Xiaoling, Han, Xueyao, Ji, Linong
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aged, 80 and over
Arteries
Arteriosclerosis
Asian Continental Ancestry Group
Atherosclerosis
Atherosclerosis - complications
Atherosclerosis - pathology
Biochemical characteristics
Biochemistry
Biology and Life Sciences
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - etiology
Cardiovascular Diseases - pathology
Carotid arteries
Consent
Coronary vessels
Cross-Sectional Studies
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - pathology
Diabetic retinopathy
Endocrinology
Ethics
Female
Glucose
Health risks
Hemoglobin
Humans
Hyperlipidemia
Male
Medicine and Health Sciences
Metabolism
Middle Aged
Mortality
Odds Ratio
Patients
Prevalence studies (Epidemiology)
Regression analysis
Regression models
Retrospective Studies
Risk analysis
Risk Factors
Risk management
Stroke
Studies
Type 2 diabetes
Ultrasonic imaging
Urine
Variables
Variance analysis
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The prevalence of type 2 diabetes is increasing rapidly in the young population. The clinical characteristics and risk factors for young type 2 diabetes patients with atherosclerosis are not fully explicated. The aim of the present study was to investigate various clinical and biochemical characteristics of young type 2 diabetic patients with atherosclerosis. This was a cross-sectional study. The study involved 2199 hospitalized patients with type 2 diabetes. The young patients were classified into the atherosclerotic group or the non-atherosclerotic group, and we also enrolled an older group with peripheral atherosclerosis disease and an age of at least 45 years. Comparisons were made between the different groups to investigate the cardiovascular and metabolic risk profiles of young type 2 diabetes patients with atherosclerosis. We also used logistic regression models to assess the atherosclerosis risk factors for young patients. Compared to older type 2 diabetes patients with atherosclerosis, young patients with atherosclerosis had more deleterious profiles of weight and hyperlipidemia. Only age and diabetes duration were found to be significant independent risk factors for atherosclerosis in young patients. The ratio of the presence of atherosclerosis in the lower extremity arteries alone was significantly higher in young patients than older patients (26.4% vs. 14.0%, P = 0.000). Young type 2 diabetes patients with atherosclerosis have more adverse cardiovascular risk profiles and inadequate control of these risk factors. Lower extremity examination is of high importance in young patients.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0159055