Global Economic Burden of Norovirus Gastroenteritis

Despite accounting for approximately one fifth of all acute gastroenteritis illnesses, norovirus has received comparatively less attention than other infectious pathogens. With several candidate vaccines under development, characterizing the global economic burden of norovirus could help funders, po...

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Bibliographic Details
Published in:PloS one 2016-04, Vol.11 (4), p.e0151219-e0151219
Main Authors: Bartsch, Sarah M, Lopman, Benjamin A, Ozawa, Sachiko, Hall, Aron J, Lee, Bruce Y
Format: Article
Language:English
Subjects:
Absenteeism
Adult
Adults
Age
Ambulatory care
Analysis
Biology and life sciences
Caliciviridae Infections - economics
Care and treatment
Child
Children
Computer applications
Computer Simulation
Control
Control methods
Cost analysis
Cost estimates
Cost of Illness
Costs
Diarrhea
Disease control
Disease prevention
Dosage and administration
Economic aspects
Economic models
Estimates
Gastroenteritis
Gastroenteritis - economics
Health aspects
Health Care Costs
Health care expenditures
Hospitalization
Hospitals
Humans
Illnesses
Immunization
Income
Infectious diseases
Malnutrition
Medicine and Health Sciences
Models, Economic
Mortality
Norovirus
Operations research
People and Places
Prevention
Productivity
Public health
Respiratory diseases
Risk factors
Sensitivity analysis
Social aspects
Social Sciences
Systematic review
Vaccines
Viruses
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Description
Summary:Despite accounting for approximately one fifth of all acute gastroenteritis illnesses, norovirus has received comparatively less attention than other infectious pathogens. With several candidate vaccines under development, characterizing the global economic burden of norovirus could help funders, policy makers, public health officials, and product developers determine how much attention and resources to allocate to advancing these technologies to prevent and control norovirus. We developed a computational simulation model to estimate the economic burden of norovirus in every country/area (233 total) stratified by WHO region and globally, from the health system and societal perspectives. We considered direct costs of illness (e.g., clinic visits and hospitalization) and productivity losses. Globally, norovirus resulted in a total of $4.2 billion (95% UI: $3.2-5.7 billion) in direct health system costs and $60.3 billion (95% UI: $44.4-83.4 billion) in societal costs per year. Disease amongst children
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0151219