Endurance Exercise Enhances the Effect of Strength Training on Muscle Fiber Size and Protein Expression of Akt and mTOR

Reports concerning the effect of endurance exercise on the anabolic response to strength training have been contradictory. This study re-investigated this issue, focusing on training effects on indicators of protein synthesis and degradation. Two groups of male subjects performed 7 weeks of resistan...

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Bibliographic Details
Published in:PloS one 2016-02, Vol.11 (2), p.e0149082-e0149082
Main Authors: Kazior, Zuzanna, Willis, Sarah J, Moberg, Marcus, Apró, William, Calbet, José A L, Holmberg, Hans-Christer, Blomstrand, Eva
Format: Article
Language:English
Subjects:
Activities of daily living
Adult
AKT protein
Analysis
Biology and Life Sciences
Biopsy
Dietary fiber
Durability
Endurance
Exercise
Gene expression
Health aspects
Health sciences
Humans
Hypertrophy
Kinases
Male
Medicin/Teknik
Medicine and Health Sciences
Medicine/Technology
Muscle Fibers, Skeletal - physiology
Muscle Proteins - metabolism
Muscle Strength
Musculoskeletal system
Oxygen
Oxygen Consumption
Oxygen uptake
Physical Endurance
Protein biosynthesis
Protein synthesis
Proteins
Proto-Oncogene Proteins c-akt - metabolism
Research and Analysis Methods
Resistance Training
RNA, Messenger - genetics
RNA, Messenger - metabolism
Rodents
Signal Transduction
Sports training
Strength training
TOR protein
TOR Serine-Threonine Kinases - metabolism
Training
Weight training
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Summary:Reports concerning the effect of endurance exercise on the anabolic response to strength training have been contradictory. This study re-investigated this issue, focusing on training effects on indicators of protein synthesis and degradation. Two groups of male subjects performed 7 weeks of resistance exercise alone (R; n = 7) or in combination with preceding endurance exercise, including both continuous and interval cycling (ER; n = 9). Muscle biopsies were taken before and after the training period. Similar increases in leg-press 1 repetition maximum (30%; P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0149082