Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

The broadly neutralizing HIV monoclonal antibodies (bnMAbs) PG9, PG16, PGT151, and PGT152 have been shown earlier to occasionally display an unusual virus neutralization profile with a non-sigmoidal slope and a plateau at

Saved in:
Bibliographic Details
Published in:PLoS pathogens 2015-08, Vol.11 (8), p.e1005110-e1005110
Main Authors: McCoy, Laura E, Falkowska, Emilia, Doores, Katie J, Le, Khoa, Sok, Devin, van Gils, Marit J, Euler, Zelda, Burger, Judith A, Seaman, Michael S, Sanders, Rogier W, Schuitemaker, Hanneke, Poignard, Pascal, Wrin, Terri, Burton, Dennis R
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
Antibodies, Monoclonal - immunology
Antibodies, Neutralizing - immunology
Binding sites
Chromatography
Cloning
Consortia
Data collection
Funding
Health aspects
HEK293 Cells
HIV
HIV (Viruses)
HIV Antibodies - immunology
HIV-1 - immunology
Host-virus relationships
Human immunodeficiency virus
Humans
Immunoglobulins
Infections
Monoclonal antibodies
Neutralization Tests
Observations
Proteins
Vaccines
Viruses
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The broadly neutralizing HIV monoclonal antibodies (bnMAbs) PG9, PG16, PGT151, and PGT152 have been shown earlier to occasionally display an unusual virus neutralization profile with a non-sigmoidal slope and a plateau at
ISSN:1553-7374
1553-7366
1553-7374
DOI:10.1371/journal.ppat.1005110