Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia

MLL-rearranged acute lymphoblastic leukemia (ALL) in infants (

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Bibliographic Details
Published in:PloS one 2015-03, Vol.10 (3), p.e0120326-e0120326
Main Authors: van der Linden, Marieke H, Seslija, Lidija, Schneider, Pauline, Driessen, Emma M C, Castro, Patricia Garrido, Stumpel, Dominique J P M, van Roon, Eddy, de Boer, Jasper, Williams, Owen, Pieters, Rob, Stam, Ronald W
Format: Article
Language:English
Subjects:
Acute lymphoblastic leukemia
Acute lymphocytic leukemia
Adult
Breast cancer
Cancer genetics
Cell culture
Cell cycle
Cell Line, Tumor
Child, Preschool
Childrens health
Cluster Analysis
Comparative analysis
DNA Methylation
Female
Gene expression
Gene Expression Profiling
Gene Expression Regulation, Leukemic
Gene Knockdown Techniques
Gene silencing
Genes
Health aspects
Hematology
Humans
Infants
Leukemia
Lymphatic leukemia
Medical prognosis
Medical research
Myeloid-Lymphoid Leukemia Protein - genetics
Oncogene Proteins, Fusion - genetics
Oncology
Pediatrics
Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics
Prognosis
Promoter Regions, Genetic
Protein expression
Proteins
RNA, Small Interfering - genetics
siRNA
Transcription
Transcription (Genetics)
Transcriptome
Translocation, Genetic
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Description
Summary:MLL-rearranged acute lymphoblastic leukemia (ALL) in infants (
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0120326