Bioartificial heart: a human-sized porcine model--the way ahead

A bioartificial heart is a theoretical alternative to transplantation or mechanical left ventricular support. Native hearts decellularized with preserved architecture and vasculature may provide an acellular tissue platform for organ regeneration. We sought to develop a tissue-engineered whole-heart...

Full description

Bibliographic Details

Published in:	PloS one 2014-11, Vol.9 (11), p.e111591-e111591
Main Authors:	Weymann, Alexander, Patil, Nikhil Prakash, Sabashnikov, Anton, Jungebluth, Philipp, Korkmaz, Sevil, Li, Shiliang, Veres, Gabor, Soos, Pal, Ishtok, Roland, Chaimow, Nicole, Pätzold, Ines, Czerny, Natalie, Schies, Carsten, Schmack, Bastian, Popov, Aron-Frederik, Simon, André Rüdiger, Karck, Matthias, Szabo, Gabor
Format:	Article
Language:	eng
Subjects:	Animals Biology and Life Sciences Biomechanics Bioreactors Cell culture Collagen Computer simulation Control stability Coronary vessels Deoxyribonucleic acid Detergents Detergents, Synthetic DNA Elastin Electron microscopy Endothelial cells Engineering and Technology Extracellular matrix Female Fibers Fluorescence Fluorescence microscopy Guided Tissue Regeneration - methods Heart Heart diseases Heart surgery Heart transplantation Heart, Artificial Histology Hogs Hospitals Human Umbilical Vein Endothelial Cells - cytology Humans Ischemia Laboratory animals Medicin och hälsovetenskap Medicine and Health Sciences Mice Models, Animal Myocytes, Cardiac - cytology Neonates Organ culture Perfusion Physiological aspects Pulmonary arteries Regeneration Rodents Spectrophotometry Stability analysis Swine Tissue Engineering Tissue Scaffolds Transmission electron microscopy Transplantation Transplants & implants Umbilical cord Ventricle
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!