Genetic determinants of serum testosterone concentrations in men

Testosterone concentrations in men are associated with cardiovascular morbidity, osteoporosis, and mortality and are affected by age, smoking, and obesity. Because of serum testosterone's high heritability, we performed a meta-analysis of genome-wide association data in 8,938 men from seven coh...

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Bibliographic Details

Published in:	PLoS genetics 2011-10, Vol.7 (10), p.e1002313-e1002313
Main Authors:	Ohlsson, Claes, Wallaschofski, Henri, Lunetta, Kathryn L, Stolk, Lisette, Perry, John R B, Koster, Annemarie, Petersen, Ann-Kristin, Eriksson, Joel, Lehtimäki, Terho, Huhtaniemi, Ilpo T, Hammond, Geoffrey L, Maggio, Marcello, Coviello, Andrea D, Ferrucci, Luigi, Heier, Margit, Hofman, Albert, Holliday, Kate L, Jansson, John-Olov, Kähönen, Mika, Karasik, David, Karlsson, Magnus K, Kiel, Douglas P, Liu, Yongmei, Ljunggren, Osten, Lorentzon, Mattias, Lyytikäinen, Leo-Pekka, Meitinger, Thomas, Mellström, Dan, Melzer, David, Miljkovic, Iva, Nauck, Matthias, Nilsson, Maria, Penninx, Brenda, Pye, Stephen R, Vasan, Ramachandran S, Reincke, Martin, Rivadeneira, Fernando, Tajar, Abdelouahid, Teumer, Alexander, Uitterlinden, André G, Ulloor, Jagadish, Viikari, Jorma, Völker, Uwe, Völzke, Henry, Wichmann, H Erich, Wu, Tsung-Sheng, Zhuang, Wei Vivian, Ziv, Elad, Wu, Frederick C W, Raitakari, Olli, Eriksson, Anna, Bidlingmaier, Martin, Harris, Tamara B, Murray, Anna, de Jong, Frank H, Murabito, Joanne M, Bhasin, Shalender, Vandenput, Liesbeth, Haring, Robin
Format:	Article
Language:	eng
Subjects:	Adult Aged, 80 and over Aging Alleles Androgens Body Mass Index Chromosomes, Human, X - genetics Clinical Medicine Colleges & universities Confidence intervals Education Endocrinology and Diabetes Endokrinologi och diabetes Gene loci Genome-Wide Association Study Genomes Grants Health aspects Heart Humans Klinisk medicin Male Medical and Health Sciences Medicin och hälsovetenskap Medicine Men Mens health Middle Aged Mortality Nuclear Proteins - genetics Orthopedics Ortopedi Physiological aspects Polymorphism, Single Nucleotide Promoters (Genetics) Sex Hormone-Binding Globulin - genetics Testosterone Testosterone - blood
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