Severe Mycoplasma Pneumonia in Young Children with Down Syndrome

Three young children with Down syndrome developed fever, cough, wheezing, irritability, and tachypnea. They had bilateral infiltrates on their chest radiographs and developed respiratory distress, which required their hospitalization. Laboratory studies suggested that the children had mycoplasma pne...

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Bibliographic Details
Published in:Clinical pediatrics 1992-07, Vol.31 (7), p.409-412
Main Authors: Orlicek, Shari L., Walker, Michael S., Kuhls, Thomas L.
Format: Article
Language:English
Subjects:
Bacterial diseases
Bacterial diseases of the respiratory system
Biological and medical sciences
Blood Gas Analysis
Cefotaxime - administration & dosage
Cefotaxime - therapeutic use
Child, Preschool
Complement Fixation Tests
Diagnosis, Differential
Down Syndrome - complications
Erythromycin - administration & dosage
Erythromycin - therapeutic use
Human bacterial diseases
Humans
Infectious diseases
Life Sciences & Biomedicine
Male
Medical sciences
Pediatrics
Pneumonia, Mycoplasma - diagnosis
Pneumonia, Mycoplasma - drug therapy
Pneumonia, Mycoplasma - etiology
Radiography, Thoracic
Science & Technology
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Summary:Three young children with Down syndrome developed fever, cough, wheezing, irritability, and tachypnea. They had bilateral infiltrates on their chest radiographs and developed respiratory distress, which required their hospitalization. Laboratory studies suggested that the children had mycoplasma pneumonia. These children may have experienced severe mycoplasma infections early in life because of their Down syndrome-associated immune abnormalities. When young children with Down syndrome develop pneumonia, physicians should consider Mycoplasma pneumoniae as the possible etiologic agent.
ISSN:0009-9228
1938-2707
DOI:10.1177/000992289203100706