Phylogenetic Analysis of Viridans Group Streptococci Causing Endocarditis

Identification of viridans group streptococci (VGS) to the species level is difficult because VGS exchange genetic material. We performed multilocus DNA target sequencing to assess phylogenetic concordance of VGS for a well-defined clinical syndrome. The hierarchy of sequence data was often discorda...

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Bibliographic Details
Published in:Journal of Clinical Microbiology 2008-09, Vol.46 (9), p.3087-3090
Main Authors: Simmon, Keith E, Hall, Lori, Woods, Christopher W, Marco, Francesc, Miro, Jose M, Cabell, Christopher, Hoen, Bruno, Marin, Mercedes, Utili, Riccardo, Giannitsioti, Efthymia, Doco-Lecompte, Thanh, Bradley, Suzanne, Mirrett, Stanley, Tambic, Arjana, Ryan, Suzanne, Gordon, David, Jones, Phillip, Korman, Tony, Wray, Dannah, Reller, L. Barth, Tripodi, Marie-Francoise, Plesiat, Patrick, Morris, Arthur J, Lang, Selwyn, Murdoch, David R, Petti, Cathy A
Format: Article
Language:English
Subjects:
Bacteriology
Biological and medical sciences
Endocarditis, Bacterial
Endocarditis, Bacterial - microbiology
Fundamental and applied biological sciences. Psychology
Humans
Life Sciences
Microbiology
Microbiology and Parasitology
Phylogeny
Sequence Analysis, DNA
Streptococcal Infections
Streptococcal Infections - microbiology
Viridans Streptococci
Viridans Streptococci - genetics
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Summary:Identification of viridans group streptococci (VGS) to the species level is difficult because VGS exchange genetic material. We performed multilocus DNA target sequencing to assess phylogenetic concordance of VGS for a well-defined clinical syndrome. The hierarchy of sequence data was often discordant, underscoring the importance of establishing biological relevance for finer phylogenetic distinctions.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.00920-08