Evaluation of StrepB Carrot Broth versus Lim Broth for Detection of Group B Streptococcus Colonization Status of Near-Term Pregnant Women

The performance of StrepB Carrot Broth (SCB) versus group B Lim broth (LIM) for detection of group B streptococcus (GBS) colonization status in near-term pregnant women (35 to 37 weeks of gestation) was evaluated. Dually collected vaginal/rectal swabs from 279 women enrolled from a single large mate...

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Bibliographic Details
Published in:Journal of Clinical Microbiology 2008-08, Vol.46 (8), p.2780-2782
Main Authors: Church, D.L, Baxter, Heather, Lloyd, Tracie, Miller, Beverley, Elsayed, Sameer
Format: Article
Language:English
Subjects:
Adult
Bacteriological Techniques - methods
Bacteriology
Biological and medical sciences
Carrier State - microbiology
Culture Media
Female
Fundamental and applied biological sciences. Psychology
Humans
Microbiology
Miscellaneous
Predictive Value of Tests
Pregnancy
Pregnancy Complications, Infectious - microbiology
Pregnant Women
Rectum - microbiology
Sensitivity and Specificity
Streptococcus agalactiae - isolation & purification
Vagina - microbiology
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Summary:The performance of StrepB Carrot Broth (SCB) versus group B Lim broth (LIM) for detection of group B streptococcus (GBS) colonization status in near-term pregnant women (35 to 37 weeks of gestation) was evaluated. Dually collected vaginal/rectal swabs from 279 women enrolled from a single large maternity clinic were analyzed. Fifty (18%) women were colonized by GBS according to both methods. SCB had excellent diagnostic performance compared to LIM, with sensitivity, specificity, positive predictive value, and negative predictive value of 92%, 100%, 100%, and 98.3%, respectively. Improved diagnostic efficiency due to direct reporting of GBS cases based on an orange color change in the SCB decreased overall labor and material costs.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.00557-08