Factors Affecting Plasma Aluminum Concentrations in Nonexposed Workers

In this study, the distribution and determinants of plasma aluminum concentrations were examined in 71 office employees not occupationally exposed to aluminum. The samples were analyzed by Zeeman graphite furnace atomic absorption spectroscopy and were found to be log normally distributed. After usi...

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Bibliographic Details
Published in:Journal of occupational and environmental medicine 1992-10, Vol.34 (10), p.1013-1017
Main Author: House, Ronald A.
Format: Article
Language:English
Subjects:
ABSORPTION SPECTRA
Adult
ALUMINIUM
Aluminum - blood
ANIMALS
Antacids - administration & dosage
Aspirin - administration & dosage
Biological and medical sciences
BIOLOGICAL MATERIALS
BLOOD
BLOOD PLASMA
BODY FLUIDS
Carbonated Beverages
Chemical and industrial products toxicology. Toxic occupational diseases
Cooking and Eating Utensils
Deodorants
Electricity
ELEMENTS
ENVIRONMENTAL EXPOSURE
Female
Humans
Life Sciences & Biomedicine
Male
MAMMALS
MAN
MATERIALS
MATHEMATICS
Medical sciences
METABOLISM
METALS
Metals and various inorganic compounds
OCCUPATIONAL EXPOSURE
ORIGINAL ARTICLES
PERSONNEL
PRIMATES
PROBABILITY
Public, Environmental & Occupational Health
RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT
REGRESSION ANALYSIS
Science & Technology
SPECTRA
STATISTICS
Tablets, Enteric-Coated
Toxicology
VERTEBRATES 560300 > Chemicals Metabolism & Toxicology
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Summary:In this study, the distribution and determinants of plasma aluminum concentrations were examined in 71 office employees not occupationally exposed to aluminum. The samples were analyzed by Zeeman graphite furnace atomic absorption spectroscopy and were found to be log normally distributed. After using the International Federation of Clinical Chemistry (IFCC) recommended procedure for removal of likely aberrant values, the 95th percentile value was 198 nmol/L (90% CI:165-238); when those using antacids were also excluded, the 95th percentile value fell to 175 nmol/L (90% CI:147-208). Multiple regression analysis indicated that the factors most predictive of log plasma aluminum were the batch in which the sample was analyzed and the use of antacids containing aluminum. The statistical significance of the batch variable likely indicates the well-recognized problem of contamination in sampling and analyzing aluminum.
ISSN:0096-1736
1076-2752
2332-3795
1536-5948