Lung Ventilation Scanning with a New Carbon Particle Radioaerosol (Technegas): Preliminary Patient Studies

A new Tc-99m labeled carbon particle aerosol (“Technegas”) has been developed for lung ventilation scanning. This is the first reported clinical study of this agent in the United States. A total of 23 subjects were studied. Thirteen had comparative Xe-133 studies, and in seven patients pulmonary ang...

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Bibliographic Details
Published in:Clinical nuclear medicine 1990-04, Vol.15 (4), p.222-226
Main Authors: RIMKUS, DANIEL S, ASHBURN, WILLIAM L
Format: Article
Language:English
Subjects:
550602 > Medicine-- External Radiation in Diagnostics-- (1980-)
AEROSOLS
Angiography
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
Biological and medical sciences
BIOMEDICAL RADIOGRAPHY
BODY
Clinical Trials as Topic
COLLOIDS
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISPERSIONS
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
Humans
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
Investigative techniques, diagnostic techniques (general aspects)
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
Lung - diagnostic imaging
LUNGS
MAMMALS
MAN
Medical sciences
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PERFUSED ORGANS
PERTECHNETATES
Pilot Projects
PRIMATES
Pulmonary Embolism - diagnostic imaging
RADIOACTIVE AEROSOLS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
RADIOLOGY AND NUCLEAR MEDICINE
Radionuclide Imaging
Radionuclide investigations
REFRACTORY METAL COMPOUNDS
RESPIRATORY SYSTEM
Sodium Pertechnetate Tc 99m - administration & dosage
SOLS
TECHNETIUM 99
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TRANSITION ELEMENT COMPOUNDS
Ventilation-Perfusion Ratio
VERTEBRATES
XENON 133
XENON ISOTOPES
Xenon Radioisotopes
YEARS LIVING RADIOISOTOPES 550601 > Medicine-- Unsealed Radionuclides in Diagnostics
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Description
Summary:A new Tc-99m labeled carbon particle aerosol (“Technegas”) has been developed for lung ventilation scanning. This is the first reported clinical study of this agent in the United States. A total of 23 subjects were studied. Thirteen had comparative Xe-133 studies, and in seven patients pulmonary angiograms were available. The Technegas study agreed closely with the Xe-133 results in 10 out of 13 patients, while the pulmonary angiogram confirmed the Technegas and perfusion scan findings in seven out of seven cases. The Technegas scan was easily performed and well tolerated by all patients. If further clinical trials confirm these preliminary findings, Technegas may become the preferred agent for lung ventilation scanning.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199004000-00002