Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy

Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy

Patient anatomy has complicated effects on cardiac SPECT images. The authors investigated reconstruction methods which substantially reduced these effects for improved image quality. A 3D mathematical cardiac-torso (MCAT) phantom which models the anatomical structures in the thorax region were used...

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Bibliographic Details
Published in:IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States) 1994-12, Vol.41 (6), p.2838-2844
Main Authors: Tsui, B.M.W., Zhao, X.D., Gregoriou, G.K., Lalushl, D.S., Frey, E.C., Johnston, R.E., McCartney, W.H.
Format: Article
Language:eng
Subjects:
ACCURACY
Anatomical structure
Anatomy
ATTENUATION
BETA DECAY RADIOISOTOPES
Biological and medical sciences
BODY
BODY AREAS
CARDIOVASCULAR SYSTEM
CHEST
COMPUTERIZED TOMOGRAPHY
CONTROL
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
HEART
HEAVY NUCLEI
IMAGE PROCESSING
Image quality
Image reconstruction
Imaging phantoms
Investigative techniques, diagnostic techniques (general aspects)
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
Mathematical model
Medical sciences
MOCKUP
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PHANTOMS
PROCESSING
QUALITY CONTROL
RADIOISOTOPES
RADIOLOGY AND NUCLEAR MEDICINE
Radionuclide investigations
Reconstruction algorithms
SECONDS LIVING RADIOISOTOPES
Shape
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
STRUCTURAL MODELS
THALLIUM 201
THALLIUM ISOTOPES
Thorax
TOMOGRAPHY 550601 > Medicine-- Unsealed Radionuclides in Diagnostics
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Description
Summary:Patient anatomy has complicated effects on cardiac SPECT images. The authors investigated reconstruction methods which substantially reduced these effects for improved image quality. A 3D mathematical cardiac-torso (MCAT) phantom which models the anatomical structures in the thorax region were used in the study. The phantom was modified to simulate variations in patient anatomy including regions of natural thinning along the myocardium, body size, diaphragmatic shape, gender, and size and shape of breasts for female patients. Distributions of attenuation coefficients and Tl-201 uptake in different organs in a normal patient were also simulated. Emission projection data were generated from the phantoms including effects of attenuation and detector response. The authors have observed the attenuation-induced artifacts caused by patient anatomy in the conventional FBP reconstructed images. Accurate attenuation compensation using iterative reconstruction algorithms and attenuation maps substantially reduced the image artifacts and improved quantitative accuracy. The authors conclude that reconstruction methods which accurately compensate for nonuniform attenuation can substantially reduce image degradation caused by variations in patient anatomy in cardiac SPECT.< >
ISSN:0018-9499
1558-1578