Recent Advances in Iron Oxide Nanoparticles (IONPs): Synthesis and Surface Modification for Biomedical Applications

In recent years, extensive researches were devoted to iron oxide nanoparticles (IONPs), including magnetite (Fe 3 O 4 ) and maghemite (γ-Fe 2 O 3 ), due to their low toxicity and cost, in addition to their unique physicochemical and magnetic properties. In this review, we present a brief introductio...

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Bibliographic Details
Published in:Journal of superconductivity and novel magnetism 2019-04, Vol.32 (4), p.779-795
Main Authors: Noqta, Osama Abu, Aziz, Azlan Abdul, Usman, Ibrahim Adamu, Bououdina, M.
Format: Article
Language:English
Subjects:
Characterization and Evaluation of Materials
CLASSIFICATION
Condensed Matter Physics
DRUG DELIVERY
IRON OXIDES
Magnetic Materials
MAGNETIC PROPERTIES
Magnetism
MAGNETITE
MEDICINE
MODIFICATIONS
NANOPARTICLES
NANOSCIENCE AND NANOTECHNOLOGY
ORGANIC MATTER
Physics
Physics and Astronomy
PVP
Review
REVIEWS
SHAPE
Strongly Correlated Systems
Superconductivity
SURFACES
SYNTHESIS
TOXICITY
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Summary:In recent years, extensive researches were devoted to iron oxide nanoparticles (IONPs), including magnetite (Fe 3 O 4 ) and maghemite (γ-Fe 2 O 3 ), due to their low toxicity and cost, in addition to their unique physicochemical and magnetic properties. In this review, we present a brief introduction on IONPs in terms of classification and properties. Because the synthesis approach and surface modification are found to be key factors for better control of particle morphology and shape, as well as to produce monodispersed IONPs, which have direct influence on their properties and applications, particular emphasis will be given to the chemical synthesis methods and surface modifications by several organic materials such as polyvinylpyrrolidone (PVP), chitosan, and cetyltrimethylammonium bromide (CTAB). Recent trends and future prospects in this research field are also discussed.
ISSN:1557-1939
1557-1947
DOI:10.1007/s10948-018-4939-6