Percutaneous transcatheter aortic disc Valve prosthesis implantation : A feasibility study

Over the past 30 years there have been experimental efforts at catheter-based management of aortic valve regurgitation with the idea of extending treatment to nonsurgical candidates. A new catheter-based aortic valve design is described. The new catheter-delivered valve consists of a stent-based val...

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Bibliographic Details
Published in:Cardiovascular and interventional radiology 2000-09, Vol.23 (5), p.384-388
Main Authors: SOCHMAN, Jan, PEREGRIN, Jan H, PAVCNIK, Dusan, TIMMERMANS, Hans, RÖSCH, Josef
Format: Article
Language:English
Subjects:
Animals
AORTA
Aortic Valve Insufficiency - therapy
Biological and medical sciences
Cardiology. Vascular system
DESIGN
DOGS
Endocardial and cardiac valvular diseases
FEASIBILITY STUDIES
Heart
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation
Medical sciences
Prosthesis Design
RADIOLOGY AND NUCLEAR MEDICINE
Stents
VALVES
VASCULAR DISEASES
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Description
Summary:Over the past 30 years there have been experimental efforts at catheter-based management of aortic valve regurgitation with the idea of extending treatment to nonsurgical candidates. A new catheter-based aortic valve design is described. The new catheter-delivered valve consists of a stent-based valve cage with locking mechanism and a prosthetic flexible tilting valve disc. The valve cage is delivered first followed by deployment and locking of the disc. In acute experiments, valve implantation was done in four dogs. Valve implantation was successful in all four animals. The implanted valve functioned well for the duration of the experiments (up to 3 hr). The study showed the implantation feasibility and short-term function of the tested catheter-based aortic disc valve. Further experimental studies are warranted.
ISSN:0174-1551
1432-086X
DOI:10.1007/s002700010060