“Candidatus Paraporphyromonas polyenzymogenes” encodes multi-modular cellulases linked to the type IX secretion system

In Nature, obligate herbivorous ruminants have a close symbiotic relationship with their gastrointestinal microbiome, which proficiently deconstructs plant biomass. Despite decades of research, lignocellulose degradation in the rumen has thus far been attributed to a limited number of culturable mic...

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Bibliographic Details
Published in:Microbiome 2018-03, Vol.6 (1)
Main Authors: Naas, A. E., Solden, L. M., Norbeck, A. D., Brewer, H., Hagen, L. H., Heggenes, I. M., McHardy, A. C., Mackie, R. I., Paša-Tolić, L., Arntzen, M. Ø., Eijsink, V. G. H., Koropatkin, N. M., Hess, M., Wrighton, K. C., Pope, P. B.
Format: Article
Language:English
Subjects:
Bacteroidetes
Carbohydrate-active enzymes
Cellulases
Environmental Molecular Sciences Laboratory
Type IX secretion system
Online Access:Get full text
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Summary:In Nature, obligate herbivorous ruminants have a close symbiotic relationship with their gastrointestinal microbiome, which proficiently deconstructs plant biomass. Despite decades of research, lignocellulose degradation in the rumen has thus far been attributed to a limited number of culturable microorganisms. Here, we combine meta-omics and enzymology to identify and describe a novel Bacteroidetes family (“Candidatus MH11”) composed entirely of uncultivated strains that are predominant in ruminants and only distantly related to previously characterized taxa.
ISSN:2049-2618
2049-2618