Satellite Cells Isolated from Adult Hanwoo Muscle Can Proliferate and Differentiate into Myoblasts and Adipose-like Cells

This study examined whether adult bovine muscle satellite cells from 30-month-old Hanwoo cattle are multipotential. The satellite cells were found to have the potential to proliferate and differentiate into myoblasts with the formation of multinucleated cells. In addition, treatment with the peroxis...

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Published in:Molecules and cells 2006, 22(2), , pp.239-245
Main Authors: Kook, S.H. (Chonbuk National University, Jeonju, Republic of Korea), Choi, K.C. (Korea University, Seoul, Republic of Korea), Son, Y.O. (Chonbuk National University, Jeonju, Republic of Korea), Lee, K.Y. (Chonbuk National University, Jeonju, Republic of Korea), Hwang, I.H. (Chonbuk National University, Jeonju, Republic of Korea), Lee, H.J. (National Livestock Research Institute, RDA, Suwon, Republic of Korea), Chang, J.S. (Korea National Open University, Seoul, Republic of Korea), Choi, I.H. (Yeungnam University, Gyeongsan, Republic of Korea), Lee, J.C. (Chonbuk National University, Jeonju, Republic of Korea), E-mail: leejc88@chonbuk.ac.kr
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Language:eng
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Summary:This study examined whether adult bovine muscle satellite cells from 30-month-old Hanwoo cattle are multipotential. The satellite cells were found to have the potential to proliferate and differentiate into myoblasts with the formation of multinucleated cells. In addition, treatment with the peroxisome proliferator activating receptor-γ (PPARγ) agonist, rosiglitazone, promoted their trans-differentiation into adipocytes with significant increases in glycerol accumulation and glycerol-3-phosphate dehydrogenase activity.
ISSN:1016-8478
0219-1032