A STUDY OF THE EFFECTS OF STATIC AND EXTREMELY LOW FREQUENCY MAGNETIC FIELDS ON LIPID PEROXIDATION PRODUCTS IN SUBCELLULAR FIBROBLAST FRACTIONS

Cultured fibroblasts isolated from murine livers by tissue trypsinization were exposed to a static magnetic field (0.490 T) and to extremely low frequency (ELF) magnetic field (50 Hz, 0.020 T). The cultures were exposed to magnetic fields on four consecutive days for exposure times of 2, 4, 8, 16, 3...

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Bibliographic Details
Published in:Electromagnetic biology and medicine 2002, Vol.21 (2), p.161-168
Main Authors: Kula, Bogus aw, Sobczak, Andrzej, Ku ka, Rafa
Format: Article
Language:English
Subjects:
Cellular fractions-microsomal, mitochondrial and nuclear
ELF magnetic field
Fibroblast cultures
Lipid peroxidation
Malondialdehyde (MDA)
Static magnetic field
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Summary:Cultured fibroblasts isolated from murine livers by tissue trypsinization were exposed to a static magnetic field (0.490 T) and to extremely low frequency (ELF) magnetic field (50 Hz, 0.020 T). The cultures were exposed to magnetic fields on four consecutive days for exposure times of 2, 4, 8, 16, 32, and 64 min. After such exposures and obtaining of fibroblast subcellular fractions, lipid peroxidation product-malondialdehyde (MDA) was measured. Increased peroxidation of fibroblasts' membrane structures exposed to an ELF magnetic field was observed in subcellular fractions-microsomal, mitochondrial, and nuclear. No changes in peroxidation of membrane structures were found in fibroblasts exposed to a static magnetic field.
ISSN:1536-8378
1536-8386
DOI:10.1081/JBC-120006789