Integrated optical computing: system-on-chip for surface plasmon resonance imaging

This paper presents a photodetection system for surface plasmon resonance (SPR) sensing that integrates optical computing with each pixel, thus enabling optical regression processing for sensing biological and chemical agents. The focus of this effort has been to upgrade a previous, low resolution,...

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Bibliographic Details
Main Authors: Johnston, M.M.W., Wilson, D.M., Boosh, K.S., Cramer, J.
Format: Conference Proceeding
Language:English
Subjects:
Biomedical optical imaging
Integrated optics
Optical computing
Optical imaging
Optical refraction
Optical sensors
Plasmons
Refractive index
Resonance
System-on-a-chip
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Description
Summary:This paper presents a photodetection system for surface plasmon resonance (SPR) sensing that integrates optical computing with each pixel, thus enabling optical regression processing for sensing biological and chemical agents. The focus of this effort has been to upgrade a previous, low resolution, proof-of-concept approach to system-on-chip refractive index detection by SPR based systems. The next generation chip presented here contains five more pixels and seven more bits of resolution than the original proof of concept system. A refractive index resolution of 0.0002 RI is possible with the system presented here, as opposed to 0.0010 RI for the previous hardware and 0.0005 RI for previous software-level processing of SPR data.
ISSN:0271-4302
2158-1525
DOI:10.1109/ISCAS.2005.1465379