Genetic Diversity Among Candida albicans Isolates Associated with Vertical Transmission in Preterm Triplets

We report a case of congenital candidiasis in triplets, in the context of premature labor at 25 weeks gestation, without symptomatic vaginitis or chorioamnionitis. All three infants died as a result of prematurity, aggravated by systemic candidiasis. Multi-locus sequence typing confirmed vertical tr...

Full description

Saved in:
Bibliographic Details
Published in:Mycopathologia (1975) 2014-10, Vol.178 (3-4), p.285-290
Main Authors: Hoarau, Gautier, Bougnoux, Marie-Elisabeth, Fily, Antoine, François, Nadine, Loridant, Séverine, Jawhara, Samir, d’Enfert, Christophe, Poulain, Daniel, Sendid, Boualem
Format: Article
Language:English
Subjects:
Adult
Biological diversity
Biomedical and Life Sciences
Blood
Candida albicans
Candida albicans - classification
Candida albicans - genetics
Candida albicans - isolation & purification
Candidemia
Candidemia - congenital
Candidemia - microbiology
Candidemia - transmission
Catheters
Congenital diseases
DNA, Fungal
DNA, Fungal - chemistry
DNA, Fungal - genetics
Eukaryotic Microbiology
Fatal Outcome
Female
Genetic aspects
Genetic disorders
Genetic diversity
Genetic Variation
Genotype
Humans
Infants (Premature)
Infectious Disease Transmission, Vertical
Life Sciences
Medical Microbiology
Microbial Ecology
Microbiology
Microbiology and Parasitology
Multilocus Sequence Typing
Mycological Typing Techniques
Mycology
Mycoses
Plant Sciences
Pregnancy
Premature Birth
Premature labor
Respiratory distress syndrome
Skin
Triplets
Vagina
Yeast
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We report a case of congenital candidiasis in triplets, in the context of premature labor at 25 weeks gestation, without symptomatic vaginitis or chorioamnionitis. All three infants died as a result of prematurity, aggravated by systemic candidiasis. Multi-locus sequence typing confirmed vertical transmission of Candida albicans from the mother to the triplets and revealed a slight diversity among the strains isolated from the neonates.
ISSN:0301-486X
1573-0832
DOI:10.1007/s11046-014-9803-z