Electroanatomic characterization of post-infarct scars comparison with 3-dimensional myocardial scar reconstruction based on magnetic resonance imaging

This study was designed to compare electroanatomic mapping (EAM) and magnetic resonance imaging (MRI) with delayed contrast enhancement (DCE) data for delineation of post-infarct scars. Electroanatomic substrate mapping is an important step in the post-infarct ventricular tachycardia (VT) ablation s...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2008-09, Vol.52 (10), p.839-842
Main Authors: Codreanu, Andrei, Odille, Freddy, Aliot, Etienne, Marie, Pierre-Yves, Magnin-Poull, Isabelle, Andronache, Marius, Mandry, Damien, Djaballah, Wassila, Régent, Denis, Felblinger, Jacques, de Chillou, Christian
Format: Article
Language:English
Subjects:
Acquisitions & mergers
Aged
Bioinformatics
Body Surface Potential Mapping
Body Surface Potential Mapping - instrumentation
Body Surface Potential Mapping - methods
Cardiology
Catheter Ablation
Catheters
Computer Science
Electrocardiography
Electrophysiologic Techniques, Cardiac
Endocardium
Female
Heart attacks
Heart Ventricles
Heart Ventricles - pathology
Humans
Imaging, Three-Dimensional
Imaging, Three-Dimensional - instrumentation
Life Sciences
Magnetic Resonance Imaging
Magnetic Resonance Imaging - instrumentation
Male
Myocardial Infarction
Myocardial Infarction - complications
Myocardial Infarction - diagnosis
Myocardial Infarction - physiopathology
Myocardium
Myocardium - pathology
NMR
Nuclear magnetic resonance
Prospective Studies
Quantitative Methods
Sinuses
Tachycardia, Ventricular
Tachycardia, Ventricular - etiology
Tachycardia, Ventricular - physiopathology
Time Factors
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Description
Summary:This study was designed to compare electroanatomic mapping (EAM) and magnetic resonance imaging (MRI) with delayed contrast enhancement (DCE) data for delineation of post-infarct scars. Electroanatomic substrate mapping is an important step in the post-infarct ventricular tachycardia (VT) ablation strategy, but this technique has not yet been compared with a gold-standard noninvasive tool informing on the topography and transmural extent of myocardial scars in humans. Ten patients (9 men, age 71 +/- 10 years) admitted for post-infarct VT ablation underwent both a left ventricle DCE MRI and a sinus-rhythm 3-dimensional (3D) (CARTO) EAM (Biosense Webster, Johnson & Johnson, Diamond Bar, California). A 3D color-coded MRI-reconstructed left ventricular endocardial shell was generated to display scar data (intramural location and transmural extent). A matching process allocated any CARTO point to its corresponding position on the MRI map. Electrogram (EGM) characteristics were then evaluated in relation to scar data. A spiky EGM morphology, a reduced unipolar or bipolar EGM voltage amplitude (
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2008.05.038