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Hepatic steatosis in HIV‐HCV coinfected patients in France: comparison with HCV monoinfected patients matched for body mass index and HCV genotype

Summary Background  Significance of steatosis in HIV‐HCV coinfection remains controversial. Aim  To compare the prevalence and predictors of hepatic steatosis between HIV‐HCV and HCV patients matched for steatosis known determinants. Methods  A total of 564 HCV‐naive patients undergoing liver biopsy...

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Bibliographic Details
Published in:Alimentary Pharmacology and Therapeutics 2007-12, Vol.26 (11‐12), p.1489-1498
Main Authors: CASTÉRA, L., LOKO, M. A., LE BAIL, B., COFFIE, P., DE LEDINGHEN, V., TRIMOULET, P., WINNOCK, M., DABIS, F., NEAU, D.
Format: Article
Language:English
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Summary:Summary Background  Significance of steatosis in HIV‐HCV coinfection remains controversial. Aim  To compare the prevalence and predictors of hepatic steatosis between HIV‐HCV and HCV patients matched for steatosis known determinants. Methods  A total of 564 HCV‐naive patients undergoing liver biopsy were studied: 137 with HIV‐HCV coinfection and 427 with HCV monoinfection, among whom 137 were matched for age, gender, body mass index and HCV genotype. Results  Steatosis of any grade (67.1% vs. 41.6%, P 
ISSN:0269-2813
1365-2036
0953-0673
DOI:10.1111/j.1365-2036.2007.03533.x