CD44 is a key player in non-alcoholic steatohepatitis

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Bibliographic Details
Published in:Journal of hepatology 2017-08, Vol.67 (2), p.328-338
Main Authors: Patouraux, Stéphanie, Rousseau, Déborah, Bonnafous, Stéphanie, Lebeaupin, Cynthia, Luci, Carmelo, Canivet, Clémence M, Schneck, Anne-Sophie, Bertola, Adeline, Saint-Paul, Marie-Christine, Iannelli, Antonio, Gugenheim, Jean, Anty, Rodolphe, Tran, Albert, Bailly-Maitre, Béatrice, Gual, Philippe
Format: Article
Language:English
Subjects:
Adipose tissue
Adult
Alanine
Alanine transaminase
Animal models
Animals
Bariatric Surgery
Biomarkers
Biomarkers - metabolism
Biopsy
CCR2 protein
CD44
CD44 antigen
Cell activation
Choline
Disease Models, Animal
Fatty acids
Fatty liver
Female
Fibrosis
Gastroenterology and Hepatology
Hepatitis
Hepatocytes
Humans
Hyaluronan Receptors
Hyaluronan Receptors - blood
Hyaluronan Receptors - deficiency
Hyaluronan Receptors - genetics
Hyaluronan Receptors - metabolism
Inflammation
Inflammatory diseases
Life Sciences
Lipopolysaccharides
Liver
Liver - immunology
Liver - metabolism
Liver - pathology
Liver diseases
Macrophages
Macrophages - immunology
Macrophages - metabolism
Macrophages - pathology
Male
MCP1
Methionine
Mice
Mice, Inbred C57BL
Mice, Knockout
Middle Aged
Monocyte chemoattractant protein 1
NAFLD
NASH
Non-alcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease - etiology
Non-alcoholic Fatty Liver Disease - metabolism
Non-alcoholic Fatty Liver Disease - pathology
Nutrient deficiency
Obesity
Obesity, Morbid
Obesity, Morbid - blood
Obesity, Morbid - metabolism
Obesity, Morbid - surgery
Steatosis
Surgery
Transaminase
Up-Regulation
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Description
Summary:Graphical abstract
ISSN:0168-8278
1600-0641
DOI:10.1016/j.jhep.2017.03.003