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COVID-19 outcomes in patients with multiple sclerosis: Understanding changes from 2020 to 2022

Background: Epidemiologic studies on coronavirus disease 2019 (COVID-19) in patients with multiple sclerosis (pwMS) have focused on the first waves of the pandemic until early 2021. Objectives: We aimed to extend these data from the onset of the pandemic to the global coverage by vaccination in summ...

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Published in:Multiple sclerosis 2024-03, Vol.30 (3), p.381-395
Main Authors: Jeantin, Lina, Januel, Edouard, Labauge, Pierre, Maillart, Elisabeth, de Seze, Jérôme, Zéphir, Hélène, Pelletier, Jean, Kerschen, Philippe, Biotti, Damien, Heinzlef, Olivier, Guilloton, Laurent, Bensa, Caroline, Théaudin, Marie, Vukusic, Sandra, Casez, Olivier, Maurousset, Aude, Laplaud, David, Berger, Eric, Lebrun-Frenay, Christine, Bourre, Bertrand, Branger, Pierre, Stankoff, Bruno, Clavelou, Pierre, Thouvenot, Eric, Manchon, Eric, Moreau, Thibault, Sellal, François, Zedet, Mickaël, Papeix, Caroline, Louapre, Céline
Format: Article
Language:English
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Summary:Background: Epidemiologic studies on coronavirus disease 2019 (COVID-19) in patients with multiple sclerosis (pwMS) have focused on the first waves of the pandemic until early 2021. Objectives: We aimed to extend these data from the onset of the pandemic to the global coverage by vaccination in summer 2022. Methods: This retrospective, multicenter observational study analyzed COVISEP registry data on reported COVID-19 cases in pwMS between January 2020 and July 2022. Severe COVID-19 was defined as hospitalization or higher severity. Results: Among 2584 pwMS with confirmed/highly suspected COVID-19, severe infection rates declined from 14.6% preomicron wave to 5.7% during omicron wave (p 
ISSN:1352-4585
1477-0970
DOI:10.1177/13524585231218149