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Encephalitis in travellers: a prospective multicentre study

Abstract Background As the epidemiology of encephalitis varies from one country to another, international travel may be an important clue for the diagnostic workout of this puzzling disease. Methods We performed an ancillary study using the ENCEIF prospective cohort conducted in 62 clinical sites in...

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Published in:Journal of travel medicine 2023-03, Vol.30 (2)
Main Authors: Picard, Léa, Mailles, Alexandra, Fillâtre, Pierre, Tattevin, Pierre, Stahl, Jean-Paul, Abgrall, Sophie, Argaud, Laurent, Argemi, Xavier, Asseray, Nathalie, Baille, Guillaume, Baldolli, Aurélie, Benghanem, Sarah, Biberon, Julien, Biron, Charlotte, Blanchet-Fourcade, Geneviève, Blot, Mathieu, Bonnetain, Anne, Botelho-Nevers, Elisabeth, Bourdain, Frédéric, Boutoille, David, Brasme, Hélène, Bruel, Cédric, Bruneel, Fabrice, Buzele, Rodolphe, Canouï, Etienne, Casenave, Philippe, Castan, Bernard, Cazanave, Charles, Cazorla, Céline, Challan-Belval, Thibault, Chavanet, Pascal, Chirouze, Catherine, Chroboczek, Tomasz, Courjon, Johan, de Broucker, Thomas, de la Blanchardière, Arnaud, de Montmollin, Etienne, Degroote, Thècle, Delaroche, Marine, Denes, Eric, Deschanvres, Colin, Diard-Detoeuf, Capucine, Dinh, Aurélien, Epaulard, Olivier, Fillatre, Pierre, Forestier, Emmanuel, Fraisse, Thibault, Froidure, Marie, Gaborit, Benjamin, Gagneux-Brunon, Amandine, Gaillard, Nicolas, Galbois, Arnaud, Godement, Mathieu, Goehringer, François, Gravier, Simon, Greigert, Valentin, Gueit, Isabelle, Guimard, Thomas, Henry, Carole, Hentzien, Maxime, Herbrecht, Jean-Etienne, Jaquet, Pierre, Jommier, Fanny, Katchatourian, Lydie, Kerneis, Solene, Krause, Jessica, Le Cam, Manuela, Le Maréchal, Marion, Le Moal, Gwenael, Le Turnier, Paul, Lecomte, Raphael, Lecompte, Anne-Sophie, Lefaucheur, Romain, Lejeune, Stéphanie, Lescure, Xavier, Lesieur, Olivier, Lesprit, Philippe, Louis, Guillaume, Lucas, Christelle, Mahieu, Rafael, Makinson, Alain, Marc, Guillaune, Maria, Alexandre, Marin, Nathalie, Martin, Aurélie, Martin-Blondel, Guillaume, Martinot, Martin, Mas, Alexandre, Mateu, Philippe, Matt, Morgan, Maulin, Laurence, Mechai, Frédéric, Mutez, Eugénie, Orain, Jérémie, Schieber-Pachart, Anne, Pansu, Nathalie, Patrat-Delon, Solene, Pavese, Patricia, Pelerin, Hélène, Pelonde-Erimée, Véronique
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Language:English
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Summary:Abstract Background As the epidemiology of encephalitis varies from one country to another, international travel may be an important clue for the diagnostic workout of this puzzling disease. Methods We performed an ancillary study using the ENCEIF prospective cohort conducted in 62 clinical sites in France from 2016 to 2019. All cases of encephalitis in adults that fulfilled a case definition derived from the International Encephalitis Consortium were included. Travellers were defined as patients who spent at least one night in a foreign country within the last six months. Results Of the 494 encephalitis patients enrolled, 69 (14%) were travellers. As compared to non-travellers, they were younger (median age, 48 years [interquartile range, 36–69] vs 66 [49–76], P 
ISSN:1195-1982
1708-8305
DOI:10.1093/jtm/taac145