Association between passive smoking and atopic dermatitis in dogs

•Dogs share the same environment as humans and may serve as sentinels for human health.•Passive smoking is often associated with the development of atopic dermatitis in children.•There is an association between high levels of passive smoking and atopic dermatitis in dogs.•The dog is a relevant model...

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Bibliographic Details
Published in:Food and chemical toxicology 2014-04, Vol.66, p.329-333
Main Authors: Ka, D., Marignac, G., Desquilbet, L., Freyburger, L., Hubert, B., Garelik, D., Perrot, S.
Format: Article
Language:English
Subjects:
Allergic diseases
Animal biology
Animals
Atopic dermatitis
Biological and medical sciences
Canine
Dermatitis, Atopic - etiology
Dogs
Female
Food toxicology
Immunopathology
Life Sciences
Malassezia
Male
Medical sciences
Second-hand smoking
Skin allergic diseases. Stinging insect allergies
Smoking
Third-hand smoking
Tobacco
Tobacco Smoke Pollution
Tobacco, tobacco smoking
Toxicology
Veterinary medicine and animal Health
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Summary:•Dogs share the same environment as humans and may serve as sentinels for human health.•Passive smoking is often associated with the development of atopic dermatitis in children.•There is an association between high levels of passive smoking and atopic dermatitis in dogs.•The dog is a relevant model to explore risk factors in atopic dermatitis.•Results also provide smokers with pets with an additional reason for giving up smoking. Onset of atopic dermatitis and occurrence of related skin lesions are influenced by various environmental factors in humans, and companion animals. Several studies have demonstrated an association between passive smoking and the development of atopic dermatitis in children. This association has never been investigated in the dog to our knowledge. We enrolled 161 dogs seen at dermatology and vaccination consultations over a six-month period for this study. Dog owners were asked to complete a questionnaire, to evaluate the exposure of the dog to tobacco smoke. The atopic or non-atopic status of the dog was assessed on the basis of Favrot’s criteria (history, clinical examination and cutaneous cytology for Malassezia). Analysis of the data for the 161 dogs enrolled revealed a significant association between high levels of passive exposure to tobacco smoke (cigarette consumption divided by the area of the home) and the presence of atopic dermatitis in the dogs (OR, 4.38; 95% CI, 1.10–17.44; p=0.03; NNH (number needed to harm) 3, 95% CI 2–52). The prevalence of atopic dermatitis showed a slight, but non-significant association with breed predisposition. Dogs with high levels of exposure to tobacco smoke may have a higher risk of atopic dermatitis than non-exposed dogs.
ISSN:0278-6915
1873-6351
DOI:10.1016/j.fct.2014.01.015