Rheological investigation of the influence of dextran on the self-assembly of lysine derivatives in water/dimethylsulfoxide mixtures

Hybrid molecular/macromolecular gels were formulated by mixing amino-acid based gelators with dextran, a nonionic bacterial polysaccharide, in mixtures of water and dimethylsulfoxide. Gelators were hydrophobic derivatives of L-lysine in which the Nα was acylated with dodecanoic acid and the Nε was a...

Full description

Saved in:
Bibliographic Details
Published in:Colloids and surfaces. A, Physicochemical and engineering aspects Physicochemical and engineering aspects, 2021-09, Vol.625, p.126908, Article 126908
Main Authors: Rangel Euzcateguy, Géraldine, Parajua-Sejil, Caroline, Marchal, Philippe, Chapron, David, Averlant-Petit, Marie-Christine, Stefan, Loïc, Pickaert, Guillaume, Durand, Alain
Format: Article
Language:English
Subjects:
Chemical Sciences
Dextran
Hybrid gel
Kinetics
Lysine
Rheology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hybrid molecular/macromolecular gels were formulated by mixing amino-acid based gelators with dextran, a nonionic bacterial polysaccharide, in mixtures of water and dimethylsulfoxide. Gelators were hydrophobic derivatives of L-lysine in which the Nα was acylated with dodecanoic acid and the Nε was acylated by benzoyloxycarbonyl or o-chloro-benzoyloxycarbonyl group. Increasing dextran concentration led to a decrease of the stationary values of storage and loss modulus of the gels. In addition, gel formation was slowed down upon increasing dextran concentration. Nevertheless, the characteristics of aggregates as well as their kinetics of growth, as deduced from rheological data, remained identical to those observed with gelator alone (mainly linear fractal aggregates and unidirectional growing mechanism) whatever dextran concentration. Raman microscopy confirmed conclusions drawn from rheological data. It was concluded that dextran macromolecules were mainly at the origin of steric hindrance with supramolecular aggregates. [Display omitted] •Aqueous/organic hybrid colloidal gels were formed by lysine derivatives and dextran.•Kinetics of gel formation was monitored using rheology and Raman microscopy.•Hybrid gels formation occurred by unidirectional growth of mainly linear aggregates.•Dextran slowed down crowding of aggregates and decreased the final rheological moduli.
ISSN:0927-7757
1873-4359
DOI:10.1016/j.colsurfa.2021.126908