Exclusion of two candidate genes, Spnb-2 and Ddc, for the wobbler spinal muscular atrophy gene on proximal mouse Chromosome 11

In order to test the possible involvement of Spnb-2 and Ddc in the wobbler disease, we have studied their segregation in an interspecies cross in direct comparison with that of the wr gene. An approach that combined the analysis of a functional candidate gene with mapping information has led to the...

Full description

Saved in:
Bibliographic Details
Published in:Mammalian genome 1994-03, Vol.5 (3), p.163-166
Main Authors: Lengeling, A., Zimmer, W. E., Goodman, S. R., Ma, Y., Bloom, M. L., Bruneau, G., Krieger, M., Thibault, J., Kaupmann, K., Jockusch, H.
Format: Article
Language:English
Subjects:
Life Sciences
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In order to test the possible involvement of Spnb-2 and Ddc in the wobbler disease, we have studied their segregation in an interspecies cross in direct comparison with that of the wr gene. An approach that combined the analysis of a functional candidate gene with mapping information has led to the molecular identification of the myotonia gene adr in the mouse.
ISSN:0938-8990
1432-1777
DOI:10.1007/BF00352348