Which PrP haplotypes in a French sheep population are the most susceptible to atypical scrapie

A French sheep case control study has been organised to estimate the effects of the PrP haplotypes on resistance to atypical scrapie. The ALHQ and AFRQ haplotypes are significantly more susceptible than the others.

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Bibliographic Details
Published in:Archives of virology 2007-06, Vol.152 (6), p.1229-1232
Main Authors: Moreno, C. R, Moazami-Goudarzi, K, Laurent, P, Cazeau, G, Andreoletti, O, Chadi, S, Elsen, J.-M, Calavas, D
Format: Article
Language:English
Subjects:
Animals
Base Sequence
Biological and medical sciences
Datasets
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
DNA - genetics
France
Fundamental and applied biological sciences. Psychology
Genotype & phenotype
Haplotypes
Human viral diseases
Infectious diseases
Life Sciences
Medical sciences
Microbiology
Microbiology and Parasitology
Miscellaneous
Neurology
Polymorphism, Genetic
Prions - genetics
Scrapie - genetics
Sheep
Sheep - genetics
Software
Surveillance
Viral diseases
Viral diseases of the nervous system
Virology
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Description
Summary:A French sheep case control study has been organised to estimate the effects of the PrP haplotypes on resistance to atypical scrapie. The ALHQ and AFRQ haplotypes are significantly more susceptible than the others.
ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-007-0956-7