Methicillin-susceptible Staphylococcus aureus clonal complex 398: high prevalence and geographical heterogeneity in bone and joint infection and nasal carriage

The prevalence of clonal complex (CC) 398 methicillin-susceptible Staphylococcus aureus (MSSA) was unexpectedly high among bone and joint infections (BJIs) and nasal-colonizing isolates in France, with surprising geographical heterogeneity. With none of the major, most-known staphylococcal virulence...

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Published in:Clinical microbiology and infection 2014-10, Vol.20 (10), p.O772-O775
Main Authors: Valour, F., Tasse, J., Trouillet-Assant, S., Rasigade, J.-P., Lamy, B., Chanard, E., Verhoeven, P., Decousser, J.-W., Marchandin, H., Bés, M., Chidiac, C., Vandenesch, F., Ferry, T., Laurent, F.
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Language:eng
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Summary:The prevalence of clonal complex (CC) 398 methicillin-susceptible Staphylococcus aureus (MSSA) was unexpectedly high among bone and joint infections (BJIs) and nasal-colonizing isolates in France, with surprising geographical heterogeneity. With none of the major, most-known staphylococcal virulence genes, MSSA CC398 BJI was associated with lower biological inflammatory syndrome and lower treatment failure rates.
ISSN:1198-743X
1469-0691