Multiple Calvarial Lytic Lesions: A Differential Diagnosis from Early Medieval France (5th to 7th c. AD)

ABSTRACT A skull from the early French Medieval period presenting multiple destructive lesions is investigated. The study of this presumably young female skull suggests a series of possible diagnoses using macroscopic features, standard radiography, CT, and 3D analysis. After a review of the paleopa...

Full description

Saved in:
Bibliographic Details
Published in:International journal of osteoarchaeology 2014-09, Vol.24 (5), p.665-674
Main Authors: Bauduer, F., Bessou, M., Guyomarc'h, P., Mercier, C., Castex, D.
Format: Article
Language:English
Subjects:
Archaeology and Prehistory
differential diagnosis
Forensic pathology
Forensic radiography
Humanities and Social Sciences
lytic lesions
Merovingian
Middle Ages
paleopathology
radiology
skull
Three dimensional imaging
Tomography
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:ABSTRACT A skull from the early French Medieval period presenting multiple destructive lesions is investigated. The study of this presumably young female skull suggests a series of possible diagnoses using macroscopic features, standard radiography, CT, and 3D analysis. After a review of the paleopathological and medical literature, the debate focuses on several malignant disorders (cancerous metastases, multiple myeloma), Langerhans cell histiocytosis, and other benign conditions such as infection (especially tuberculosis) or sarcoidosis. Although the definite diagnosis of such paleopathological lesions is not straightforward, Langerhans cell histiocytosis is the most probable diagnosis. Copyright © 2012 John Wiley & Sons, Ltd.
ISSN:1047-482X
1099-1212
DOI:10.1002/oa.2256