Isolated Cryptorchidism: No Evidence for Involvement of Genes Underlying Idiopathic Hypogonadotropic Hypogonadism

► We investigated the defects in , , , , , and in 54 subjects with isolated cryptorchidism. ► Two subjects carried heterozygous mutations (Q106R and R262Q), but these changes were also present in controls with similar frequency. ► None of the subjects carried mutation(s) in , , , or . ► It is unlike...

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Bibliographic Details
Published in:Molecular and cellular endocrinology 2011-07, Vol.341 (1-2)
Main Authors: Laitinen, Eeva-Maria, Tommiska, Johanna, Virtanen, Helena E., Oehlandt, Heidi, Koivu, Rosanna, Vaaralahti, Kirsi, Toppari, Jorma, Raivio, Taneli
Format: Article
Language:English
Subjects:
Biochemistry, Molecular Biology
Life Sciences
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Summary:► We investigated the defects in , , , , , and in 54 subjects with isolated cryptorchidism. ► Two subjects carried heterozygous mutations (Q106R and R262Q), but these changes were also present in controls with similar frequency. ► None of the subjects carried mutation(s) in , , , or . ► It is unlikely that mutations in these genes would significantly contribute to the prevalence of isolated cryptorchidism.
ISSN:0303-7207
0303-7207
DOI:10.1016/j.mce.2011.05.015