Subcutaneous anti- globulin application is a safe treatment option of immune thrombocytopenia in children

Subcutaneous (sc) administration of anti- seems to offer the same efficacy as intravenous administration but with less side effects. Here we report our experience with sc anti- for pediatric immune thrombocytopenia (ITP). A total of 12 children with a median age of 11.2 years had been treated by sc...

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Bibliographic Details
Published in:Annals of hematology 2009-10, Vol.89 (4), p.415-418
Main Authors: Trebo, Monika M., Frey, Eva, Gadner, Helmut, Minkov, Milen
Format: Article
Language:English
Online Access:Get full text
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Summary:Subcutaneous (sc) administration of anti- seems to offer the same efficacy as intravenous administration but with less side effects. Here we report our experience with sc anti- for pediatric immune thrombocytopenia (ITP). A total of 12 children with a median age of 11.2 years had been treated by sc anti-. They received a median of 2 sc anti- applications (range 1–31) with a dosage of 250–375 IE/kg body weight. Only in one out of a total of 102 single applications, a minimal and self-limited side effect (chills) had been observed. The mean platelet count was almost doubled after sc anti- ( 
ISSN:0939-5555
1432-0584
DOI:10.1007/s00277-009-0848-x