Bioactive Poly(ethylene terephthalate) Fibers and Fabrics:  Grafting, Chemical Characterization, and Biological Assessment

The grafting of poly(sodium styrene sulfonate) (pNaSS) onto ozone-treated poly(ethylene terephthalate) (PET) fabric surfaces was characterized by X-ray photoelectron spectroscopy and toluidine blue colorimetry. Significant amounts of pNaSS were grafted over the range of experimental conditions exami...

Full description

Saved in:
Bibliographic Details
Published in:Biomacromolecules 2007-11, Vol.8 (11), p.3317-3325
Main Authors: Pavon-Djavid, G, Gamble, L. J, Ciobanu, M, Gueguen, V, Castner, D. G, Migonney, V
Format: Article
Language:English
Subjects:
Adsorption
Applied sciences
Cell Adhesion - drug effects
Cell Line
Cell Proliferation - drug effects
Cell Shape - drug effects
Exact sciences and technology
Fibers and threads
Forms of application and semi-finished materials
Humans
Kinetics
Ozone - chemistry
Polyethylene Terephthalates - chemistry
Polyethylene Terephthalates - pharmacology
Polymer industry, paints, wood
Polystyrenes - chemistry
Serum Albumin - chemistry
Technology of polymers
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The grafting of poly(sodium styrene sulfonate) (pNaSS) onto ozone-treated poly(ethylene terephthalate) (PET) fabric surfaces was characterized by X-ray photoelectron spectroscopy and toluidine blue colorimetry. Significant amounts of pNaSS were grafted over the range of experimental conditions examined in this study (30−120 min of ozonation, reaction at 65 or 70 °C, and reaction times up to 240 min). Within these ranges the amount of grafted pNaSS increased with both ozonation time and reaction temperature. The amount of grafted pNaSS increased over the first 60 min of reaction, then remained relatively constant from 60 to 240 min. For the biological experiments pNaSS-grafted samples were prepared with 30 min of ozonation and 60 min of reaction at a grafting temperature of 70 °C. The ozonation time was limited to 30 min to minimize any possible degradation of the PET fabrics by the ozonation treatment. The pNaSS-grafted PET surface adsorbed a factor of 4 more compared to the nongrafted surfaces. The strength of fibroblast adhesion was an order of magnitude higher on pNaSS-grafted PET fabrics compared to that on nongrafted PET fabrics. This difference in the cell attachment was correlated to the cell spreading, which was better and more homogeneous on the grafted fibers compared to the nongrafted fibers. Fibroblasts adhered more strongly on surfaces precoated with normal human plasma compared to surfaces precoated with 10% fetal calf serum in Dulbecco's modified Eagle's medium.
ISSN:1525-7797
1526-4602
DOI:10.1021/bm070344i