Loading…
In vivo characterization of the mechanical properties of human skin derived from MRI and indentation techniques
The human skin is an exceedingly complex and multi-layered material. This paper aims to introduce the application of the finite element analysis (FEA) to the in vivo characterization of the non-linear mechanical behaviour of three human skin layers. Indentation tests combined with magnetic resonance...
Saved in:
| Published in: | Computer methods in biomechanics and biomedical engineering 2007-12, Vol.10 (6), p.401-407 |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c349t-48cfc1a550e9e43bdfba1a83783a097500a19ce5f155e48da9611d2bb5f758213 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c349t-48cfc1a550e9e43bdfba1a83783a097500a19ce5f155e48da9611d2bb5f758213 |
| container_end_page | 407 |
| container_issue | 6 |
| container_start_page | 401 |
| container_title | Computer methods in biomechanics and biomedical engineering |
| container_volume | 10 |
| creator | Tran, H. V. Charleux, F. Rachik, M. Ehrlacher, A. Ho Ba Tho, M. C. |
| description | The human skin is an exceedingly complex and multi-layered material. This paper aims to introduce the application of the finite element analysis (FEA) to the in vivo characterization of the non-linear mechanical behaviour of three human skin layers. Indentation tests combined with magnetic resonance imaging (MRI) technique have been performed on the left dorsal forearm of a young man in order to reveal the mechanical behaviour of all skin layers. Using MRI images processing and a pre and post processor allows to make numerically individualized 2D model which consists of three skin layers and the muscles. FEA has been applied to simulate indentation tests. Neo-Hookean slightly compressible material model of two material constants (C
10
, K) has been used to model the mechanical behaviour of the three skin layers and the muscles. The identification of material model parameters was done by applying Levenberg-Marquardt algorithm (LMA). Our methodology of identification provides a range of values for each constant. Range of values of different material properties of epidermis, dermis, hypodermis are respectively, C10
E
= 0.12 ± 0.06 MPa, C10
D
= 1.11 ± 0.09 MPa, C10
H
= 0.42 ± 0.05 KPa, K
E
= 5.45 ± 1.7 MPa, K
D
= 29.6 ± 1,28 MPa, K
H
= 36.0 ± O.9 KPa. |
| doi_str_mv | 10.1080/10255840701550287 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_00203722v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>70114333</sourcerecordid><originalsourceid>FETCH-LOGICAL-c349t-48cfc1a550e9e43bdfba1a83783a097500a19ce5f155e48da9611d2bb5f758213</originalsourceid><addsrcrecordid>eNqFUU1vFCEYJkZj6-oP8GI4mXgYCwwsTOKlaWq7yTYmRs_kHQay6AyswK7WX18ms9FDY-QCeZ-PvA8PQq8peU-JIheUMCEUJ5JQIQhT8gk6p1yuG8VE97S-K95UAjtDL3L-RghRVPHn6IxK1dG15OcobgI--mPEZgcJTLHJ_4biY8DR4bKzeLIVCd7AiPcp7m0q3uYZ3B0mCDh_9wEPVXW0A3YpTvju8wZDGLAPgw1l8SrVJPgfB5tfomcOxmxfne4V-vrx-svVbbP9dLO5utw2puVdabgyzlCoqWxnedsPrgcKqpWqBdJJQQjQzljhanDL1QDdmtKB9b1wUihG2xV6t_juYNT75CdI9zqC17eXWz3PCGGklYwdZ-7bhVsDzjsWPfls7DhCsPGQdf1eytt6VoguRJNizsm6P86U6LkR_aiRqnlzMj_0kx3-Kk4VVIJcCD64mCb4GdM46AL3Y0wuQTA-P7bV5Vepyg__Vbb_3uwBpGirqg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70114333</pqid></control><display><type>article</type><title>In vivo characterization of the mechanical properties of human skin derived from MRI and indentation techniques</title><source>Taylor and Francis Science and Technology Collection</source><creator>Tran, H. V. ; Charleux, F. ; Rachik, M. ; Ehrlacher, A. ; Ho Ba Tho, M. C.</creator><creatorcontrib>Tran, H. V. ; Charleux, F. ; Rachik, M. ; Ehrlacher, A. ; Ho Ba Tho, M. C.</creatorcontrib><description>The human skin is an exceedingly complex and multi-layered material. This paper aims to introduce the application of the finite element analysis (FEA) to the in vivo characterization of the non-linear mechanical behaviour of three human skin layers. Indentation tests combined with magnetic resonance imaging (MRI) technique have been performed on the left dorsal forearm of a young man in order to reveal the mechanical behaviour of all skin layers. Using MRI images processing and a pre and post processor allows to make numerically individualized 2D model which consists of three skin layers and the muscles. FEA has been applied to simulate indentation tests. Neo-Hookean slightly compressible material model of two material constants (C
10
, K) has been used to model the mechanical behaviour of the three skin layers and the muscles. The identification of material model parameters was done by applying Levenberg-Marquardt algorithm (LMA). Our methodology of identification provides a range of values for each constant. Range of values of different material properties of epidermis, dermis, hypodermis are respectively, C10
E
= 0.12 ± 0.06 MPa, C10
D
= 1.11 ± 0.09 MPa, C10
H
= 0.42 ± 0.05 KPa, K
E
= 5.45 ± 1.7 MPa, K
D
= 29.6 ± 1,28 MPa, K
H
= 36.0 ± O.9 KPa.</description><identifier>ISSN: 1025-5842</identifier><identifier>EISSN: 1476-8259</identifier><identifier>DOI: 10.1080/10255840701550287</identifier><identifier>PMID: 17891674</identifier><language>eng</language><publisher>England: Taylor & Francis Group</publisher><subject>Anisotropy ; Biomechanical Phenomena - methods ; Computer Simulation ; Elasticity ; FEM ; Hardness ; Hardness Tests - methods ; Humans ; Hyper-elastic ; Identification method ; Image Interpretation, Computer-Assisted - methods ; Indentation ; Life Sciences ; Magnetic resonance imaging ; Magnetic Resonance Imaging - methods ; Mechanical properties human skin ; Models, Biological ; Skin - anatomy & histology ; Skin Physiological Phenomena ; Viscosity</subject><ispartof>Computer methods in biomechanics and biomedical engineering, 2007-12, Vol.10 (6), p.401-407</ispartof><rights>Copyright Taylor & Francis Group, LLC 2007</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c349t-48cfc1a550e9e43bdfba1a83783a097500a19ce5f155e48da9611d2bb5f758213</citedby><cites>FETCH-LOGICAL-c349t-48cfc1a550e9e43bdfba1a83783a097500a19ce5f155e48da9611d2bb5f758213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,786,790,891,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17891674$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-00203722$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Tran, H. V.</creatorcontrib><creatorcontrib>Charleux, F.</creatorcontrib><creatorcontrib>Rachik, M.</creatorcontrib><creatorcontrib>Ehrlacher, A.</creatorcontrib><creatorcontrib>Ho Ba Tho, M. C.</creatorcontrib><title>In vivo characterization of the mechanical properties of human skin derived from MRI and indentation techniques</title><title>Computer methods in biomechanics and biomedical engineering</title><addtitle>Comput Methods Biomech Biomed Engin</addtitle><description>The human skin is an exceedingly complex and multi-layered material. This paper aims to introduce the application of the finite element analysis (FEA) to the in vivo characterization of the non-linear mechanical behaviour of three human skin layers. Indentation tests combined with magnetic resonance imaging (MRI) technique have been performed on the left dorsal forearm of a young man in order to reveal the mechanical behaviour of all skin layers. Using MRI images processing and a pre and post processor allows to make numerically individualized 2D model which consists of three skin layers and the muscles. FEA has been applied to simulate indentation tests. Neo-Hookean slightly compressible material model of two material constants (C
10
, K) has been used to model the mechanical behaviour of the three skin layers and the muscles. The identification of material model parameters was done by applying Levenberg-Marquardt algorithm (LMA). Our methodology of identification provides a range of values for each constant. Range of values of different material properties of epidermis, dermis, hypodermis are respectively, C10
E
= 0.12 ± 0.06 MPa, C10
D
= 1.11 ± 0.09 MPa, C10
H
= 0.42 ± 0.05 KPa, K
E
= 5.45 ± 1.7 MPa, K
D
= 29.6 ± 1,28 MPa, K
H
= 36.0 ± O.9 KPa.</description><subject>Anisotropy</subject><subject>Biomechanical Phenomena - methods</subject><subject>Computer Simulation</subject><subject>Elasticity</subject><subject>FEM</subject><subject>Hardness</subject><subject>Hardness Tests - methods</subject><subject>Humans</subject><subject>Hyper-elastic</subject><subject>Identification method</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>Indentation</subject><subject>Life Sciences</subject><subject>Magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Mechanical properties human skin</subject><subject>Models, Biological</subject><subject>Skin - anatomy & histology</subject><subject>Skin Physiological Phenomena</subject><subject>Viscosity</subject><issn>1025-5842</issn><issn>1476-8259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNqFUU1vFCEYJkZj6-oP8GI4mXgYCwwsTOKlaWq7yTYmRs_kHQay6AyswK7WX18ms9FDY-QCeZ-PvA8PQq8peU-JIheUMCEUJ5JQIQhT8gk6p1yuG8VE97S-K95UAjtDL3L-RghRVPHn6IxK1dG15OcobgI--mPEZgcJTLHJ_4biY8DR4bKzeLIVCd7AiPcp7m0q3uYZ3B0mCDh_9wEPVXW0A3YpTvju8wZDGLAPgw1l8SrVJPgfB5tfomcOxmxfne4V-vrx-svVbbP9dLO5utw2puVdabgyzlCoqWxnedsPrgcKqpWqBdJJQQjQzljhanDL1QDdmtKB9b1wUihG2xV6t_juYNT75CdI9zqC17eXWz3PCGGklYwdZ-7bhVsDzjsWPfls7DhCsPGQdf1eytt6VoguRJNizsm6P86U6LkR_aiRqnlzMj_0kx3-Kk4VVIJcCD64mCb4GdM46AL3Y0wuQTA-P7bV5Vepyg__Vbb_3uwBpGirqg</recordid><startdate>200712</startdate><enddate>200712</enddate><creator>Tran, H. V.</creator><creator>Charleux, F.</creator><creator>Rachik, M.</creator><creator>Ehrlacher, A.</creator><creator>Ho Ba Tho, M. C.</creator><general>Taylor & Francis Group</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope></search><sort><creationdate>200712</creationdate><title>In vivo characterization of the mechanical properties of human skin derived from MRI and indentation techniques</title><author>Tran, H. V. ; Charleux, F. ; Rachik, M. ; Ehrlacher, A. ; Ho Ba Tho, M. C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-48cfc1a550e9e43bdfba1a83783a097500a19ce5f155e48da9611d2bb5f758213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Anisotropy</topic><topic>Biomechanical Phenomena - methods</topic><topic>Computer Simulation</topic><topic>Elasticity</topic><topic>FEM</topic><topic>Hardness</topic><topic>Hardness Tests - methods</topic><topic>Humans</topic><topic>Hyper-elastic</topic><topic>Identification method</topic><topic>Image Interpretation, Computer-Assisted - methods</topic><topic>Indentation</topic><topic>Life Sciences</topic><topic>Magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Mechanical properties human skin</topic><topic>Models, Biological</topic><topic>Skin - anatomy & histology</topic><topic>Skin Physiological Phenomena</topic><topic>Viscosity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tran, H. V.</creatorcontrib><creatorcontrib>Charleux, F.</creatorcontrib><creatorcontrib>Rachik, M.</creatorcontrib><creatorcontrib>Ehrlacher, A.</creatorcontrib><creatorcontrib>Ho Ba Tho, M. C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Computer methods in biomechanics and biomedical engineering</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tran, H. V.</au><au>Charleux, F.</au><au>Rachik, M.</au><au>Ehrlacher, A.</au><au>Ho Ba Tho, M. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In vivo characterization of the mechanical properties of human skin derived from MRI and indentation techniques</atitle><jtitle>Computer methods in biomechanics and biomedical engineering</jtitle><addtitle>Comput Methods Biomech Biomed Engin</addtitle><date>2007-12</date><risdate>2007</risdate><volume>10</volume><issue>6</issue><spage>401</spage><epage>407</epage><pages>401-407</pages><issn>1025-5842</issn><eissn>1476-8259</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>The human skin is an exceedingly complex and multi-layered material. This paper aims to introduce the application of the finite element analysis (FEA) to the in vivo characterization of the non-linear mechanical behaviour of three human skin layers. Indentation tests combined with magnetic resonance imaging (MRI) technique have been performed on the left dorsal forearm of a young man in order to reveal the mechanical behaviour of all skin layers. Using MRI images processing and a pre and post processor allows to make numerically individualized 2D model which consists of three skin layers and the muscles. FEA has been applied to simulate indentation tests. Neo-Hookean slightly compressible material model of two material constants (C
10
, K) has been used to model the mechanical behaviour of the three skin layers and the muscles. The identification of material model parameters was done by applying Levenberg-Marquardt algorithm (LMA). Our methodology of identification provides a range of values for each constant. Range of values of different material properties of epidermis, dermis, hypodermis are respectively, C10
E
= 0.12 ± 0.06 MPa, C10
D
= 1.11 ± 0.09 MPa, C10
H
= 0.42 ± 0.05 KPa, K
E
= 5.45 ± 1.7 MPa, K
D
= 29.6 ± 1,28 MPa, K
H
= 36.0 ± O.9 KPa.</abstract><cop>England</cop><pub>Taylor & Francis Group</pub><pmid>17891674</pmid><doi>10.1080/10255840701550287</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1025-5842 |
| ispartof | Computer methods in biomechanics and biomedical engineering, 2007-12, Vol.10 (6), p.401-407 |
| issn | 1025-5842 1476-8259 |
| language | eng |
| recordid | cdi_hal_primary_oai_HAL_hal_00203722v1 |
| source | Taylor and Francis Science and Technology Collection |
| subjects | Anisotropy Biomechanical Phenomena - methods Computer Simulation Elasticity FEM Hardness Hardness Tests - methods Humans Hyper-elastic Identification method Image Interpretation, Computer-Assisted - methods Indentation Life Sciences Magnetic resonance imaging Magnetic Resonance Imaging - methods Mechanical properties human skin Models, Biological Skin - anatomy & histology Skin Physiological Phenomena Viscosity |
| title | In vivo characterization of the mechanical properties of human skin derived from MRI and indentation techniques |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-22T22%3A22%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=In%20vivo%20characterization%20of%20the%20mechanical%20properties%20of%20human%20skin%20derived%20from%20MRI%20and%20indentation%20techniques&rft.jtitle=Computer%20methods%20in%20biomechanics%20and%20biomedical%20engineering&rft.au=Tran,%20H.%20V.&rft.date=2007-12&rft.volume=10&rft.issue=6&rft.spage=401&rft.epage=407&rft.pages=401-407&rft.issn=1025-5842&rft.eissn=1476-8259&rft_id=info:doi/10.1080/10255840701550287&rft_dat=%3Cproquest_hal_p%3E70114333%3C/proquest_hal_p%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c349t-48cfc1a550e9e43bdfba1a83783a097500a19ce5f155e48da9611d2bb5f758213%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=70114333&rft_id=info:pmid/17891674&rfr_iscdi=true |