Neurological and Psychiatric Manifestations of Long COVID-19 and Their [[sup.18]F]FDG PET Findings: A Review

For more than two years, lingering sequalae of COVID-19 have been extensively investigated. Approximately 10% of individuals infected by COVID-19 have been found to experience long-term symptoms termed “long COVID-19”. The neurological and psychiatric manifestations of long COVID-19 are of particula...

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Bibliographic Details
Published in:Diagnostics (Basel) 2023-07, Vol.13 (14)
Main Authors: Hameed, Rizwanullah, Bahadur, Anuradha Rosario, Singh, Shashi Bhushan, Sher, Juwairah, Todua, Maia, Moradi, Leah (Mahsa), Bastakoti, Sanjiv, Arslan, Maeen, Ajmal, Hanfa, Lee, Gha Young, Ayubcha, Cyrus, Werner, Thomas J, Alavi, Abass, Revheim, Mona-Elisabeth
Format: Article
Language:English
Subjects:
PET imaging
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Summary:For more than two years, lingering sequalae of COVID-19 have been extensively investigated. Approximately 10% of individuals infected by COVID-19 have been found to experience long-term symptoms termed “long COVID-19”. The neurological and psychiatric manifestations of long COVID-19 are of particular concern. While pathogenesis remains unclear, emerging imaging studies have begun to better elucidate certain pathological manifestation. Of specific interest is imaging with [[sup.18]F]FDG PET which directly reflects cellular glycolysis often linked to metabolic and inflammatory processes. Seeking to understand the molecular basis of neurological features of long COVID-19, this review encompasses the most recent [[sup.18]F]FDG PET literature in this area.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics13142353