Hypermetabolic Calcified Lymph Nodes on [.sup.18]Fludeoxyglucose-Positron Emission Tomography/Computed Tomography in a Case of Treated Ovarian Cancer Recurrence: Residual Disease or Benign Formation?/Tedavi Edilmis Over Kanseri Nuksunde [.sup.18]Florodeoksiglikoz-Pozitron Emisyon Tomografisi/Bilgisayarli Tomografi ile Saptanan Hipermetabolik Kalsifiye Lenf Nodlari: Reziduel Hastalik mi? Benign Olusum mu?

The contribution of positron emission tomography/computed tomography (PET/CT) with [.sup.18]F-fludeoxyglucose (FDG) in evaluating ovarian cancer recurrence even after a prolonged disease-free interval, and in therapy response is well-described. Calcifications observed in CT, although usually attribu...

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Published in:Molecular imaging and radionuclide therapy 2016-06, Vol.25 (2), p.91
Main Authors: Nikaki, Alexandra, Alexopoulos, Athanasios, Vlachou, Fani, Filippi, Vasiliki, Andreou, loannis, Rapti, Vasiliki, Gogos, Konstantinos, Dalianis, Konstantinos, Efthymiadou, Roxani, Prassopoulos, Vassilios
Format: Article
Language:English
Subjects:
Chemotherapy
Diagnosis
Health aspects
Lymph nodes
Ovarian cancer
Positron emission tomography
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Summary:The contribution of positron emission tomography/computed tomography (PET/CT) with [.sup.18]F-fludeoxyglucose (FDG) in evaluating ovarian cancer recurrence even after a prolonged disease-free interval, and in therapy response is well-described. Calcifications observed in CT, although usually attributed to benign conditions, may actually represent active disease. Such an example of calcified formations is psammoma bodies. We present a case of 56-y. o. patient with ovarian cancer relapse at the supraclavicular area 18 years after complete response and disease-free interval. The patient received chemotherapy and underwent [.sup.18]F-FDG-PET/CT for the evaluation of treatment response. Both CT corrected and uncorrected PET images showed hypermetabolism in the massively calcified lymph nodes in the neck, mediastinum, axilla and abdomen, indicative of active residual disease. Keywords: [.sup.18]F-fludeoxyglucose, ovarian cancer, lymph nodes [.sup.18]Florodeoksiglikoz-pozitron emisyon tomografisi/bilgisayarli tomografinin ([.sup.18]F-FDG PET/BT) over kanserinde tedavi yanitini ve uzun bir hastaliksiz aradan sonra nuksu degerlendirmede katkisi ortaya konulmustur. Genellikle benign durumlara atfedilmesine ragmen BT'de gozlenen kalsifikasyonlari aslinda aktif hastalik bulgusu olabilir. Buna benzer kalsifiye olusumlara bir ornek psammoma cisimleridir. Biz 56 yasinda, tedaviye tam yanit ve 18 yillik hastaliksiz sagkalim sonrasi supraklavikuler alanda nuks ile saptanan bir nuks over kanseri hastasini sunduk. Hasta kemoterapi aldi ve tedaviye cevabin degerlendirilmesi icin [.sup.18]F-FDG-PET/BT uygulandi. Hem duzeltilmis hem duzeltilmemis PET-BT goruntulerinde aktif reziduel hastaligin gostergesi olarak boyun, mediastinum, koltuk alti ve karinda kitlesel kalsifiye lenf dugumlerinde hipermetabolizma saptandi. Anahtar kelimeler: [.sup.18]F-florodeoksiglikoz, over kanseri, lenf dugumleri
ISSN:2146-1414
DOI:10.4274/mirt.22932