Biologically Active Compounds in Aqueous Extracts of Caragana jubata (Pall.) Poir

Polyphenolic compounds (flavonoids) of lyophilized aqueous extracts from Caragana jubata (Pall.) Poir. raw material from 2010 and 2015 were studied using modern HPLC-DAD-MS. Primarily mono- and diglycosides of O -hydroxylated (myricetin, quercetin, kaempferol) and O -methylated flavonols (isorhamnet...

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2018-02, Vol.51 (11), p.1014-1020
Main Authors: Kakorin, P. A., Perova, I. B., Rybakova, E. D., Éller, K. I., Ramenskaya, G. V., Pavlova, L. A., Teselkin, Yu. O.
Format: Article
Language:English
Subjects:
Isoflavones
Medicinal Plants
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Raw materials
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Summary:Polyphenolic compounds (flavonoids) of lyophilized aqueous extracts from Caragana jubata (Pall.) Poir. raw material from 2010 and 2015 were studied using modern HPLC-DAD-MS. Primarily mono- and diglycosides of O -hydroxylated (myricetin, quercetin, kaempferol) and O -methylated flavonols (isorhamnetin, laricitrin, syringetin) were identified. Long-term storage of dried raw material under standard conditions had little effect on the quantitative content of polyphenolic compounds. Acute toxicity studies of C. jubata extract showed no toxicity.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-018-1731-7