Kinetic Factors in the Synthesis of Lidocaine by Reductive Acylation on Palladium-Containing Anion Exchangers

The kinetics of lidocaine synthesis by reductive acylation on Pd-containing anion exchangers were studied. Metallized polymers were shown to be highly effective in lidocaine synthesis.

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2014-05, Vol.48 (2), p.127-130
Main Authors: Abdullaev, M. G., Abdullaeva, Z. Sh, Klyuev, M. V., Kafarova, S. S., Gebekova, Z. G.
Format: Article
Language:English
Subjects:
Acylation
Catalysis
Drug Synthesis Methods and Manufacturing Technology
Medicine
Organic Chemistry
Palladium
Pharmacology/Toxicology
Pharmacy
Production processes
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Description
Summary:The kinetics of lidocaine synthesis by reductive acylation on Pd-containing anion exchangers were studied. Metallized polymers were shown to be highly effective in lidocaine synthesis.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-014-1062-2