Maternal 25

Given the high rate of preterm birth (PTB) nationwide and data from RCTs demonstrating risk reduction with vitamin D supplementation, the Medical University of South Carolina (MUSC) implemented a new standard of care for pregnant women to receive vitamin D testing and supplementation. To determine i...

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Bibliographic Details
Published in:PloS one 2017-07, Vol.12 (7), p.e0180483
Main Authors: McDonnell, Sharon L, Baggerly, Keith A, Baggerly, Carole A, Aliano, Jennifer L, French, Christine B, Baggerly, Leo L, Ebeling, Myla D, Rittenberg, Charles S, Goodier, Christopher G, Mateus Niño, Julio F, Wineland, Rebecca J, Newman, Roger B, Hollis, Bruce W, Wagner, Carol L
Format: Article
Language:English
Subjects:
Health aspects
Measurement
Obstetrical research
Premature birth
Prevention
Risk factors
Vitamin D
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Summary:Given the high rate of preterm birth (PTB) nationwide and data from RCTs demonstrating risk reduction with vitamin D supplementation, the Medical University of South Carolina (MUSC) implemented a new standard of care for pregnant women to receive vitamin D testing and supplementation. To determine if the reported inverse relationship between maternal 25(OH)D and PTB risk could be replicated at MUSC, an urban medical center treating a large, diverse population. Medical record data were obtained for pregnant patients aged 18-45 years between September 2015 and December 2016. During this time, a protocol that included 25(OH)D testing at first prenatal visit with recommended follow-up testing was initiated. Free vitamin D supplements were offered and the treatment goal was [greater than or equal to]40 ng/mL. PTB rates (
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0180483