Cervical spinal cord infarction associated with coronavirus infectious disease

Keywords COVID-19; Spinal cord infarct; Hypercoagulable; SAR-CoV-2; Coronavirus Highlights * Clinical presentation of severe COVID-19 infection may include neurologic symptoms. * Coagulopathy due to COVID-19 leads to severe sequelae, including systemic thrombosis and multi-organ failure. * 31-Year o...

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Published in:Journal of clinical neuroscience 2021-05, Vol.87, p.89
Main Authors: Strauss, Sara B, Barie, Philip S, Bronstein, Matthew, Kahan, Joshua, Segal, Alan Z, Gibson, Cameron J, Winchell, Robert J
Format: Article
Language:eng
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Summary:Keywords COVID-19; Spinal cord infarct; Hypercoagulable; SAR-CoV-2; Coronavirus Highlights * Clinical presentation of severe COVID-19 infection may include neurologic symptoms. * Coagulopathy due to COVID-19 leads to severe sequelae, including systemic thrombosis and multi-organ failure. * 31-Year old with acute flaccid quadriparesis due to spinal cord infarction associated with severe COVID-19. Coronavirus disease (COVID-19) has a number of emerging neurological manifestations in addition to pneumonia and respiratory distress. In what follows, we describe a case of a previously healthy young man with severe COVID-19 who subsequently developed an acute flaccid paralysis. Work up revealed a lesion in his cervical spinal cord concerning for spinal infarction or transverse myelitis. He received empiric pulsed steroids without improvement. Taken together, we felt his presentation was most consistent with spinal cord infarction in the setting of critical illness with COVID-19. We believe this is a rare case of spinal cord stroke associated with COVID-19. Author Affiliation: (a) Department of Neurology, Weill Cornell Medicine, New York, NY, USA (b) Department of Surgery, Weill Cornell Medicine, New York, NY, USA (c) Department of Radiology, Weill Cornell Medicine, New York, NY, USA (d) Department of Medicine, Weill Cornell Medicine, New York, NY, USA * Corresponding author. Article History: Received 29 December 2020; Accepted 25 February 2021 Byline: Joshua Kahan (a), Cameron J. Gibson (b), Sara B. Strauss (c), Matthew Bronstein (b), Robert J. Winchell (b), Philip S. Barie (b,d), Alan Z. Segal [azs2001@med.cornell.edu] (a,*)
ISSN:0967-5868
1532-2653