Calcium antagonist-induced relaxation of the prostaglandin-F 2α response of isolated calf retinal resistance arteries

The relaxing effect of nitrendipine and D600 on isolated ring segments of calf retinal resistance arteries (i.d. ca. 200 μm) contracted with prostaglandin-F 2α (PGF 2α of high potassium solution was studied. The vessel response to both PGF 2α and potassium stimulation was dependent on extracellular...

Full description

Saved in:
Bibliographic Details
Published in:Experimental eye research 1989-03, Vol.48 (3), p.329-335
Main Authors: Nielsen, Per J., Berg Nyborg, Niels C.
Format: Article
Language:eng
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The relaxing effect of nitrendipine and D600 on isolated ring segments of calf retinal resistance arteries (i.d. ca. 200 μm) contracted with prostaglandin-F 2α (PGF 2α of high potassium solution was studied. The vessel response to both PGF 2α and potassium stimulation was dependent on extracellular calcium. Removal of extracellular calcium reduced the vessel response to PGF 2α and potassium by 85% and 98%, respectively ( P
ISSN:0014-4835
1096-0007