Asthma is characterized by more IRF5+ M1 and CD206+ M2 macrophages and less IL10+ M2-like macrophages around airways compared to healthy airways

Abstract In asthma, macrophage polarization is altered from a state associated with anti-inflammatory responses to a state associated with inflammation as compared to control. Macrophage polarization states is linked to disease severity, sex and ICS treatment.

Bibliographic Details

Published in:	Journal of allergy and clinical immunology 2016
Main Authors:	Draijer, Christina, PhD, Boorsma, Carian E., MSc, Robbe, Patricia, PhD, Timens, Wim, MD, PhD, Hylkema, Machteld N., PhD, Ten Hacken, Nick H.T., MD, PhD, van den Berge, Maarten, MD, PhD, Postma, Dirkje S., MD, PhD, Melgert, Barbro N., PhD
Format:	Article
Language:	English
Subjects:	Allergy and Immunology
Online Access:	Get full text
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