Incidence and Predictors of Left Atrial Appendage Thrombus in Patients Treated with Non-Vitamin K Oral Anticoagulants Versus Warfarin Prior to Catheter Ablation for Atrial Fibrillation

The utility of routine TEE to exclude LAA thrombus prior to AF ablation in patients treated with NOAC therapy is unclear. This single center retrospective study sought to investigate the incidence of left atrial appendage (LAA) thrombus in patients undergoing routine transesophageal echocardiography...

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Bibliographic Details
Published in:The American journal of cardiology 2016
Main Authors: Wyrembak, Joanne, MD, Campbell, Kristen B., PharmD, Steinberg, Benjamin A., MD, MHS, Bahnson, Tristram D., MD, Daubert, James P., MD, Velazquez, Eric J., MD, Samad, Zainab, MD, Atwater, Brett D., MD
Format: Article
Language:English
Subjects:
Cardiovascular
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Summary:The utility of routine TEE to exclude LAA thrombus prior to AF ablation in patients treated with NOAC therapy is unclear. This single center retrospective study sought to investigate the incidence of left atrial appendage (LAA) thrombus in patients undergoing routine transesophageal echocardiography (TEE) prior to atrial fibrillation (AF) ablation treated with warfarin or non-vitamin K oral anticoagulant (NOAC) therapy. We included 937 routine pre-AF ablation TEE procedures performed in patients treated with warfarin (n=517) or NOAC (n=420). Patients were anticoagulated without interruption for at least 4 consecutive weeks prior to the TEE. Patients treated with warfarin had lower LAA velocity and underwent TEE earlier in the study period than patients treated with NOAC ( P
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2016.12.008