Human Infection with Rickettsia felis, Kenya

To determine the cause of acute febrile illnesses other than malaria in the North Eastern Province, Kenya, we investigated rickettsial infection among patients from Garissa Provincial Hospital for 23 months during 2006-2008. Nucleic acid preparations of serum from 6 (3. 7%) of 163 patients were posi...

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Main Authors:	Richards, Allen L, Jiang, Ju, Omulo, Sylvia, Dare, Ryan, Abdirahman, Khalif, Ali, Abdile, Sharif, Shanaaz K, Feikin, Daniel R, Breiman, Robert F, Njenga, M K
Format:	Report
Language:	eng
Subjects:	Anatomy and Physiology ARTHROPODA DEOXYRIBONUCLEIC ACIDS DISEASE VECTORS FEVERS GRAM NEGATIVE BACTERIA HEADACHES HOSTS(BIOLOGY) INFECTIOUS DISEASES MALARIA Medicine and Medical Research Microbiology MUSCLES PAIN PATIENTS RICKETTSIA RICKETTSIA FELIS RICKETTSIA PROWAZEKII RICKETTSIA TYPHI SKIN DISEASES VERTEBRATES WOUNDS AND INJURIES WU0000 188M.0931.00 I.A0074
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Summary:	To determine the cause of acute febrile illnesses other than malaria in the North Eastern Province, Kenya, we investigated rickettsial infection among patients from Garissa Provincial Hospital for 23 months during 2006-2008. Nucleic acid preparations of serum from 6 (3. 7%) of 163 patients were positive for rickettsial DNA as determined by a genus specific quantitative real-time PCR and were subsequently confirmed by molecular sequencing to be positive for Rickettsia felis. The 6 febrile patients' symptoms included headache; nausea; and muscle, back, and joint pain. None of the patients had a skin rash. Pub. in Emerging Infectious Diseases, v16 n7, p1081-1086, Jul 2010.