LIPOLYTIC ACTIVITY IN THE BLOOD AFTER LIPASE INGESTION

The nature of the enzyme appearing in the blood after oral ingestion of pancreatic lipase has been studied by determining the effect of the presence of cholic acid upon the activity of some enzymes which might be present. The activity of lipoprotein and serum lipase were markedly depressed by the bi...

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Bibliographic Details
Main Authors: TIDWELL,Herbert C, McPherson,James C, Moore,W Taft, Pope,J Lon, Freeman,Alan
Format: Report
Language:English
Subjects:
BILE
BIOLOGICAL ABSORPTION
BLOOD
BLOOD CHEMISTRY
ENZYMES
FATS
FATTY ACIDS
LIPASE ENZYMES
LIPIDS
LIPOPROTEINS
PANCREAS
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Summary:The nature of the enzyme appearing in the blood after oral ingestion of pancreatic lipase has been studied by determining the effect of the presence of cholic acid upon the activity of some enzymes which might be present. The activity of lipoprotein and serum lipase were markedly depressed by the bile acid while the enzymic activity of both pancreatic lipase and the enzyme present in the blood after pancreatic lipase ingestion were greatly enhanced by the presence of cholic acid. Although the rate of fat absorption has been shown to be affected by lipase ingestion, the possibility remains that this increased lipolytic activity may play some role in clearing the blood of fat. (Author) Pub. in Proceedings of the Society for Experimental Biology and Medicine v116 p720-3 1964 (Copies not available to DDC or Clearinghouse customers).